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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by fairn on January 6, 2009, at 20:06:16
Hi im new here 23yo m ns canada, looks like a great site wondering if anyone knows any natural componds which do any of the following, i would like to compile a complete and ongoing list of natural substances which can be used for bipolar disorder and depression thanks!:
calcium channel blocker
voltage gated sodium channel modulator
protein kinase activity a or c
nmda antagonism
increase brain derived neurotrophic factor
dopamine regulation/modulation, partial agonism
acetylcholinergic agonists/increasers
glutamate activity
mitochondrial reparation/increase
corticotropin release factor (crf) inhibitor
Posted by desolationrower on January 9, 2009, at 21:06:06
In reply to natural inhibitors/blockers/activity, posted by fairn on January 6, 2009, at 20:06:16
> Hi im new here 23yo m ns canada, looks like a great site wondering if anyone knows any natural componds which do any of the following, i would like to compile a complete and ongoing list of natural substances which can be used for bipolar disorder and depression thanks!:
>for many of these, there are drugs which woudl be preferable as they are more selective. off the top of my head:
> calcium channel blocker
> voltage gated sodium channel modulator
> protein kinase activity a or c
i think gamma tocopherol blocks it> nmda antagonism
huperzine, magnesium/zinc> increase brain derived neurotrophic factor
all kinds of stuff> dopamine regulation/modulation, partial agonism
> acetylcholinergic agonists/increasers
huperzine, galantamine, nicotine> glutamate activity
glycine> mitochondrial reparation/increase
ALCAR
coq10 i think> corticotropin release factor (crf) inhibitor
>
>
>-d/r
Posted by desolationrower on January 10, 2009, at 12:51:34
In reply to Re: natural inhibitors/blockers/activity, posted by desolationrower on January 9, 2009, at 21:06:06
oh vinpocetine blocks voltages gated sodium channels
-d/r
Posted by fairn on January 10, 2009, at 13:50:17
In reply to Re: natural inhibitors/blockers/activity, posted by desolationrower on January 9, 2009, at 21:06:06
thanks so much desolationrower if thats just off the top of your head you must have extensive knowledge of this sort of stuff! if you ever come across or think of anything else please dont hesitate to post it i really havent been doing well lately and ive tried all the drugs im comfortable taking and where i live there are no open minded pdocs so nothin off label unfortunately thanks again you probably know how much just a few words can mean to a person who is "mentally ill"
Posted by desolationrower on January 11, 2009, at 2:57:56
In reply to natural inhibitors/blockers/activity, posted by fairn on January 6, 2009, at 20:06:16
If you have problems finding a doctor (i don't know what canada drug import sans a prescription laws are like) for bipolar i'd recommend
fish oil
N acetyl cysteine
lifestyle - good diet vegetables not fast food, excercise, careful with booze, make sure you have something to keep regular sleep, melatonin or antihistamine (cyproheptadine if province is otc). keeping very regular schedule is very important.
vitamin d3 especially in winter actually year round in cananda
possibly inositol as well, can have good or bad reactions though
also some evidence for just an NSAID like ibuprofen for bipolar depression
i think lecithin had a study showing positive result.
I'd also think mindfulness meditation might help improve insight on when you are becoming less stable.
hope that helps.-d/r
Posted by fairn on January 25, 2009, at 0:56:27
In reply to Re: natural inhibitors/blockers/activity, posted by desolationrower on January 11, 2009, at 2:57:56
thanks d/r those are great suggestion and actually im taking them all except vitamin d which i didnt think of but now realize (especially in Canada haha)is a really good idea!
thanks again-Clayton
Posted by Lao Tzu on January 26, 2009, at 10:47:14
In reply to Re: natural inhibitors/blockers/activity, posted by fairn on January 25, 2009, at 0:56:27
The drug Lamictal modulates sodium channels in the brain. It is a mood stabilizer. I've also read that fish oil has an effect on calcium channels. It is also a mood stabilizer.
This is the end of the thread.
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