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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by Jimmyboy on October 22, 2007, at 16:52:12
Can someone explain the connection between methylation and histamine to me? From what I gathered it seems as if you are undermethylated it means you have high levels of histamine and vice versa. Is this always the case?
If so , why? Does histamine use up methyl groups or what?
Anyway, I fit the symptoms of "overmethylation-low histamine" and it takes very large doses of niacin ( nicotinic acid) to flush and I have never take it before ( i heard this was also an idicator of low histamine- who knows)
I read you should take folic acid if you are over-methylated" , ( overmethylated = too many of each neurotransmitters??) I just don't understand why you would take folic acid, which helps make more neurotransmitters if the theory states you already have too many.
Sorry this is rambling, but I would appreciate it if anyone knew anything about this
JB
Posted by cumulative on October 23, 2007, at 22:00:45
In reply to Explain methylation / histamine connection????, posted by Jimmyboy on October 22, 2007, at 16:52:12
You should know that the "over/under-methylation" theory is just that, theory.
Folic acid has been shown in studies to be beneficial for mental-health and life-extending, as well as protective against a variety of conditions. I don't think you should alter your intake of this required nutrient due to what a bunch of hippies made up, especially when some robust clinical studies on said nutrient have been done. ;)
As for methylation, I think it's that methyl donation is needed to create the enzyme that destroys histamine. Anecdotally intake of the methyl donor TMG generally results in a reduction in allergic symptoms, inflammation, etc.
This is the end of the thread.
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