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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by flipsactown on July 29, 2004, at 4:56:37
I have been taking 30mg of Lexapro for 7 weeks and have had dramatic lifting of my unipolar depression which I noticed in my 6th week. However, although the insomnia and fatigue has greatly decreased, I am still fatigued enough that I seem to lack energy to do everyday tasks. I also take Tylenol/Codeine for chronic back pain. I started taking Glucosamine Chondroitin complex and was wondering if this will help with my chronic back pain. Are there other supplements that will help increase energy?
Thanks.FST
Posted by Slinky on July 30, 2004, at 2:59:21
In reply to Drug Induced Fatigue and Lack of Energy, posted by flipsactown on July 29, 2004, at 4:56:37
Hi
I take a powder form of vitamin b12 and vitamin c..it's taken by putting a little under the tongue..this I find is the only thing that gives me energy-without the after surge into fatigue.
Posted by Larry Hoover on August 14, 2004, at 16:45:47
In reply to Drug Induced Fatigue and Lack of Energy, posted by flipsactown on July 29, 2004, at 4:56:37
> I have been taking 30mg of Lexapro for 7 weeks and have had dramatic lifting of my unipolar depression which I noticed in my 6th week. However, although the insomnia and fatigue has greatly decreased, I am still fatigued enough that I seem to lack energy to do everyday tasks. I also take Tylenol/Codeine for chronic back pain. I started taking Glucosamine Chondroitin complex and was wondering if this will help with my chronic back pain. Are there other supplements that will help increase energy?
> Thanks.
>
> FSTThe chondroitin/glucosamine might help, and can't hurt. Pain relief might be greater with supplemental DLPA (d-,l-phenylalanine).
You can get some energy boosting from TMG (trimethylglycine), or perhaps from Enada NADH.
Lar
Posted by flipsactown on August 15, 2004, at 10:30:17
In reply to Re: Drug Induced Fatigue and Lack of Energy » flipsactown, posted by Larry Hoover on August 14, 2004, at 16:45:47
Lar,
Thanks for the response. I remember taking DLPA in the late 1980's for 2 months and did not get any relief from my chronic back pain. I even bought a book the proclaimed it as nature's natural pain killer. Has there been some improvements made to it or was 2 months not long enough to give it a chance to work?
FST
> > I have been taking 30mg of Lexapro for 7 weeks and have had dramatic lifting of my unipolar depression which I noticed in my 6th week. However, although the insomnia and fatigue has greatly decreased, I am still fatigued enough that I seem to lack energy to do everyday tasks. I also take Tylenol/Codeine for chronic back pain. I started taking Glucosamine Chondroitin complex and was wondering if this will help with my chronic back pain. Are there other supplements that will help increase energy?
> > Thanks.
> >
> > FST
>
> The chondroitin/glucosamine might help, and can't hurt. Pain relief might be greater with supplemental DLPA (d-,l-phenylalanine).
>
> You can get some energy boosting from TMG (trimethylglycine), or perhaps from Enada NADH.
>
> Lar
>
>
Posted by Larry Hoover on August 15, 2004, at 13:54:14
In reply to Re: Drug Induced Fatigue and Lack of Energy » Larry Hoover, posted by flipsactown on August 15, 2004, at 10:30:17
> Lar,
>
> Thanks for the response. I remember taking DLPA in the late 1980's for 2 months and did not get any relief from my chronic back pain. I even bought a book the proclaimed it as nature's natural pain killer. Has there been some improvements made to it or was 2 months not long enough to give it a chance to work?
>
> FSTIt seems to work synergistically with opiate pain-killers, for some people. Two months would be more than enough time to see if it works. If I'm not mistaken, you should know in two *hours*. I'll have to investigate doses for you, though.
Lar
Posted by flipsactown on August 15, 2004, at 18:38:42
In reply to Re: Drug Induced Fatigue and Lack of Energy » flipsactown, posted by Larry Hoover on August 15, 2004, at 13:54:14
I remember that I was trying not to take any narcotics, in my case Tylenol/Codeine #3, and was taking extra strength aspirin with the DLPA. So are you saying that perhaps, if I had taken DLPA with the Codeine that I may have had increased pain relief? I don't think that I tried taking DLPA with Codeine because I was wanting to get off narcotics entirely.
FST
> > Lar,
> >
> > Thanks for the response. I remember taking DLPA in the late 1980's for 2 months and did not get any relief from my chronic back pain. I even bought a book the proclaimed it as nature's natural pain killer. Has there been some improvements made to it or was 2 months not long enough to give it a chance to work?
> >
> > FST
>
> It seems to work synergistically with opiate pain-killers, for some people. Two months would be more than enough time to see if it works. If I'm not mistaken, you should know in two *hours*. I'll have to investigate doses for you, though.
>
> Lar
Posted by Larry Hoover on August 15, 2004, at 20:45:27
In reply to Re: Drug Induced Fatigue and Lack of Energy » Larry Hoover, posted by flipsactown on August 15, 2004, at 18:38:42
> I remember that I was trying not to take any narcotics, in my case Tylenol/Codeine #3, and was taking extra strength aspirin with the DLPA. So are you saying that perhaps, if I had taken DLPA with the Codeine that I may have had increased pain relief? I don't think that I tried taking DLPA with Codeine because I was wanting to get off narcotics entirely.
>
> FSTYes, that's exactly what I'm suggesting, the effects of the DLPA and the opiate are additive.
I can't find dosing recommendations, though. I'd try 2,000-3,000 mg/day, in divided doses. I don't know if it matters, but I'd also take it on an empty stomach, if tolerated.
Lar
Med Hypotheses. 2000 Oct;55(4):283-8.
DL-phenylalanine markedly potentiates opiate analgesia - an example of nutrient/pharmaceutical up-regulation of the endogenous analgesia system.Russell AL, McCarty MF.
Brampton Pain Clinic, Bramalea, Ontario, Canada.
In the author's clinical experience, concurrent treatment with DL-phenylalanine (DLPA) often appears to potentiate pain relief and also ease depression in patients receiving opiates for chronic non-malignant pain. An analysis of this phenomenon suggests that it may be mediated, at least in part, by up-regulation of the 'endogenous analgesia system' (EAS), a neural pathway that projects caudally from medullary nuclei to the dorsal horn of the spinal column; when stimulated by chronic pain or therapeutic measures such as opiates or acupuncture, the EAS suppresses activation of second-order pain-receptive neurons in the dorsal horn, and thereby alleviates pain. Since serotonin and enkephalins are key neurotransmitters in the EAS, it is reasonable to predict that measures which promote serotonin activity (such as 5-hydroxytryptophan and serotonin-reuptake inhibitors) as well as enkephalin activity (such as D-phenylalanine, an enkephalinase inhibitor) should potentiate EAS-mediated analgesia - a view consistent with much previous medical research. Comprehensive support of the EAS with well-tolerated nutrients and pharmaceuticals may amplify the analgesic efficacy of chronic opiate therapy, while enabling dosage reductions that minimize opiate side-effects. Analogously, this approach may complement the efficacy of acupuncture and other analgesic measures that activate the EAS.
Posted by flipsactown on August 15, 2004, at 23:14:04
In reply to Re: Drug Induced Fatigue and Lack of Energy » flipsactown, posted by Larry Hoover on August 15, 2004, at 20:45:27
This is the end of the thread.
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