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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by undopaminergic on April 30, 2021, at 7:11:54
Hi all,
I was wondering if anyone has tried asenapine, an atypical antipsychotic:
https://en.wikipedia.org/wiki/AsenapineIt seems to be a very "dirty" drug that hits a multitude of receptors, as an antagonist except for partial agonism at serotonin 5-HT1A.
Reading the reviews at:
https://www.drugs.com/comments/asenapine/
it seems to be a miracle drug for some people.-undopaminergic
Posted by sigismund on April 30, 2021, at 21:57:27
In reply to Asenapine, posted by undopaminergic on April 30, 2021, at 7:11:54
I was struck by this.
Posted by rjlockhart37 on May 1, 2021, at 17:19:39
In reply to Asenapine, posted by undopaminergic on April 30, 2021, at 7:11:54
i read saphris is only for manic, or manic related
Posted by rjlockhart37 on May 1, 2021, at 17:20:29
In reply to Re: Asenapine, posted by rjlockhart37 on May 1, 2021, at 17:19:39
Posted by undopaminergic on May 6, 2021, at 8:29:01
In reply to Re: Asenapine, posted by sigismund on April 30, 2021, at 21:57:27
> I was struck by this.
>
> https://www.dr-bob.org/babble/20121231/msgs/1034727.htmlHere's more:
http://www.dr-bob.org/babble/20120328/msgs/1015304.html-undopaminergic
Posted by SLS on May 7, 2021, at 8:51:47
In reply to Re: Asenapine, posted by undopaminergic on May 6, 2021, at 8:29:01
Asenapine (Saphris) has an unquestionable antidepressant and energizing effect. I watched it happen to me briefly, and watched it happen to a close friend mine who has been in remission for well over a year. Asenapine is a necessary component of her treatment. However, both of us are bipolar, so I don't know how that factors in to the equation.
- Scott
Posted by undopaminergic on May 7, 2021, at 10:26:22
In reply to Re: Asenapine, posted by SLS on May 7, 2021, at 8:51:47
> Asenapine (Saphris) has an unquestionable antidepressant and energizing effect.
>Many people report that they have do take it at night because it makes them tired. But some of those people get a good night's sleep and wake up refreshed.
> I watched it happen to me briefly, and watched it happen to a close friend mine who has been in remission for well over a year. Asenapine is a necessary component of her treatment. However, both of us are bipolar, so I don't know how that factors in to the equation.
>I'm bipolar too.
-undopaminergic
Posted by beckett2 on May 12, 2021, at 13:28:13
In reply to Re: Asenapine » SLS, posted by undopaminergic on May 7, 2021, at 10:26:22
> > Asenapine (Saphris) has an unquestionable antidepressant and energizing effect.
> >
>
> Many people report that they have do take it at night because it makes them tired. But some of those people get a good night's sleep and wake up refreshed.
>
> > I watched it happen to me briefly, and watched it happen to a close friend mine who has been in remission for well over a year. Asenapine is a necessary component of her treatment. However, both of us are bipolar, so I don't know how that factors in to the equation.
> >
>
> I'm bipolar too.
>
> -undopaminergic
>I'm part of the original thread, and I see this was before the official dx of bipolar. In retrospect, Saphris induced near mania, something unidentified at the time. I have BPll. Why do doctors hesitate to dx bipolar?
Posted by sigismund on May 12, 2021, at 23:53:53
In reply to Re: Asenapine, posted by beckett2 on May 12, 2021, at 13:28:13
> In retrospect, Saphris induced near mania
It can do that and also make you sleep like a brown bear?
Posted by beckett2 on May 12, 2021, at 23:54:43
In reply to Re: Asenapine » beckett2, posted by sigismund on May 12, 2021, at 23:53:53
G'day Sigi, apparently so!
Posted by SLS on May 14, 2021, at 15:15:20
In reply to Re: Asenapine » SLS, posted by undopaminergic on May 7, 2021, at 10:26:22
Hi UD.
> > Asenapine (Saphris) has an unquestionable antidepressant and energizing effect.
> Many people report that they have do take it at night because it makes them tired. But some of those people get a good night's sleep and wake up refreshed.
Thanks for the additional insight. That improvement in sleep is important. My friend didn't have that. I think that I forgot to say that I had been on asenapine a few years ago, but just for a few weeks. It didn't lead to remission, but its antidepressant properties were unmistakeable. I don't remember what the dosage was, but it pooped-out on me after two weeks.
- Scott
Posted by undopaminergic on May 15, 2021, at 8:29:51
In reply to Re: Asenapine » undopaminergic, posted by SLS on May 14, 2021, at 15:15:20
> Hi UD.
Hi Scott.
> > > Asenapine (Saphris) has an unquestionable antidepressant and energizing effect.
>
> > Many people report that they have do take it at night because it makes them tired. But some of those people get a good night's sleep and wake up refreshed.
>
> Thanks for the additional insight. That improvement in sleep is important. My friend didn't have that. I think that I forgot to say that I had been on asenapine a few years ago, but just for a few weeks. It didn't lead to remission, but its antidepressant properties were unmistakeable. I don't remember what the dosage was, but it pooped-out on me after two weeks.
>I'm now on 111 mg/day of lurasidone (Latuda), 37 mg in the morning and 74 mg in the evening, and I have no effect. I'm intending to try asenapine next.
-undopaminergic
This is the end of the thread.
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