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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on April 1, 2021, at 17:53:11
Amphetamine can lead to schizophrenia like symptoms. On the other hand, amphetamine acts as a TAAR1 agonist. TAAR1 agonists have shown some positive effects in schizophrenia.
I have heard case reports of amphetamine improving schizophrenia and mania. I wonder if this is the mechanism.
Linkadge
Posted by Christ_empowered on April 1, 2021, at 20:00:30
In reply to Amphetamine improving schizophrenia / mania, posted by linkadge on April 1, 2021, at 17:53:11
when vyvanse 1st hit the market, they did a small study in stable, medicated people with Schizophrenia. I think the goal was to help with depression and negative symptoms, plus whatever adverse effects this group had from meds. and...if I recall correctly, with carefully selected people and carefully controlled doses, it worked reasonably well. which...
is -not- ground breaking. ritalin was popular for those on sedating neuroleptics in the 60s. in the 50s-60s, maybe into the 70s, diet pills (read: amphetamines, sometimes amphetamine and sedative combos) were routinely used in everybody, including those with a label of Schizophrenia.
I dunno about mania. I read on some old school shrink's website that he'd used dexedrine in some cases of acute mania...something about reducing distractibility, maybe? i dunno. sounded creepy, like medical torture to me, but dude man was adamant that it 'worked,' however he chose to gauge success.
This is the end of the thread.
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