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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by paulb on August 20, 2015, at 14:42:28
hi
i have quite a wide range of experience with some gabergic drugs including pregabalin, gabapentin and benzodiazepines.
i prefer the effect of pregabalin to benzo but benzos are more reliable for me in that they work daily. i need to take breaks from pregabalinCan anyone give me any info on their experiences with either tiagabine or vigabatrin. Are they more like a benzo IN TERMS OF EFFECT not how how they work and if their addictive just their effects in particular tiagabine
many thanks for any information.
Posted by jpa on August 22, 2015, at 7:45:19
In reply to gabergic drugs, posted by paulb on August 20, 2015, at 14:42:28
I suffer GAD and insomnia. Tiagabine proved completely ineffective for anxiety or sleep. It seemed to help for a couple days, but then stopped working. A higher dose did not help. Pregabalin was better, but its impact faded quickly and it was unreliable. Eventually, pregabalin stopped working entirely. For me, benzos are only good for inducing sleep, but the sleep architecture is so disrupted that I never feel well in the morning after taking some the night before. My doctor would not prescribe vigabatrin because of the potential for serious side effects. Phenibut has been the best GABA drug for me, but like all the others, tolerance builds quickly - it is not a solution to a chronic illness.
In short, GABA related drugs have proved ineffective for me and have been a nightmare to stop taking.
That is just my personal experience. I hope you have more success with these GABA agents.
Posted by former poster on August 25, 2015, at 12:59:52
In reply to Re: gabergic drugs, posted by jpa on August 22, 2015, at 7:45:19
Would you say Phenibut is more addictive than benzo's?
Posted by phidippus on August 26, 2015, at 22:26:38
In reply to gabergic drugs, posted by paulb on August 20, 2015, at 14:42:28
Pregablin and Gabapentin are not GABAergic.
Tiagabine is. It is an SGRI or selective GABA reuptake inhibitor. It is only effective for anxiety in high doses. At these doses, the side effects of the drug become quite apparent.
Treatment with vigabatrin leads to an increase of GABA through inhibition of GABA-T. In studies vigabtrin treatment reduced anxiety and panic symptoms.
Eric
Posted by jpa on August 27, 2015, at 18:49:23
In reply to Re: gabergic drugs » jpa, posted by former poster on August 25, 2015, at 12:59:52
I found tolerance, and addiction to be a problem with both. Both were difficult to stop taking, but phenibut seemed a little easier.
This is the end of the thread.
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