Psycho-Babble Medication Thread 1081516

Shown: posts 1 to 3 of 3. This is the beginning of the thread.

Would a 5ht1a Full Agonist VS Partial Agonist

Posted by Hello321 on August 19, 2015, at 13:58:10

You might have heard on the news about the new pill, Fkibanserin, that was just approved for female sexual dysfunction. Ive read about how it works as a full agonist at the 5ht1a postsynaptic receptor, unlike mood meds like Buspar and Viibryd that work as a partial agonist at it. Flibanserin was actually intended to be a depression med when its development first began, but eventually switched to bbeing developed for sex problems. It works on the same receptors that mood meds target.

Anyway, might a full agonist be better for mood problems than the partial agonists we have today? Might it actually be better for anxiety than Buspar?

Re: Would a 5ht1a Full Agonist VS Partial Agonist

Posted by SLS on August 19, 2015, at 14:13:23

In reply to Would a 5ht1a Full Agonist VS Partial Agonist, posted by Hello321 on August 19, 2015, at 13:58:10

> You might have heard on the news about the new pill, Fkibanserin, that was just approved for female sexual dysfunction. Ive read about how it works as a full agonist at the 5ht1a postsynaptic receptor, unlike mood meds like Buspar and Viibryd that work as a partial agonist at it. Flibanserin was actually intended to be a depression med when its development first began, but eventually switched to bbeing developed for sex problems. It works on the same receptors that mood meds target.
>
> Anyway, might a full agonist be better for mood problems than the partial agonists we have today? Might it actually be better for anxiety than Buspar?

I believe Brintellix (vortioxetine) is closer to being a full agonist than a partial agonist.

- Scott

Re: Would a 5ht1a Full Agonist VS Partial Agonist

Posted by Hello321 on August 20, 2015, at 15:31:29

In reply to Re: Would a 5ht1a Full Agonist VS Partial Agonist, posted by SLS on August 19, 2015, at 14:13:23

I had read about Brintellix being a near full 5ht1a agonist. I didnt benefit from Brintellix, i still think a full agonist, like Flibanserin, might be more beneficial in some cases when it comes to mood problems. That is if one can find a doc certified to prescribe it. FDA is requiring special training before a doc is allowed to prescribe it, and for a pharmacy to be able to fill it.

This is the end of the thread.

Show another thread

Psycho-Babble Medication | Extras | FAQ

Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.