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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by kilo8 on July 19, 2015, at 20:32:22
When I tried tianeptine I was taking 12,5mg 3 times daily as suggested and felt nothing. On youtube however there are videos from people who order tianeptine online and then say that if you take 50-200mg at once your depression lifts instantly.
i don't know if such a dose would be safe though.
but it would still be interesting to know if taking a higher dose at once really has such an effect. if it did then tianeptine could be used occassionally against depression.
Posted by rjlockhart37 on July 19, 2015, at 22:54:33
In reply to Has anyone tried high-dosed tianeptine?, posted by kilo8 on July 19, 2015, at 20:32:22
yea.....i think usally in the market the use low low doses, so people won't be stupid and take a bunch of pills and have a overdose reaction.....thats why they keep the dosage small and to fit the person....
i never knew they sold it on the net.....
Posted by phidippus on August 5, 2015, at 10:40:44
In reply to Has anyone tried high-dosed tianeptine?, posted by kilo8 on July 19, 2015, at 20:32:22
Tianeptine is a mu-opioid receptor agonist-same mechanism of action as opiates.
Eric
Posted by SLS on August 12, 2015, at 5:56:10
In reply to Re: Has anyone tried high-dosed tianeptine? » kilo8, posted by phidippus on August 5, 2015, at 10:40:44
> Tianeptine is a mu-opioid receptor agonist-same mechanism of action as opiates.
Interesting.
Do you have any thoughts on the use of buprenorphine for depressive disorders?
- Scott
Posted by phidippus on August 12, 2015, at 6:49:57
In reply to Re: Has anyone tried high-dosed tianeptine? » phidippus, posted by SLS on August 12, 2015, at 5:56:10
I think Buprenorphine can be used successfully to treat depression. Buprenorphine is the strongest kappa-receptor antagonist currently available for human use, although it is also a partial agonist at the mu receptor, and the relative importance of the activity at these sites is currently unknown.
Opiates, like endorphins create a sense of well-being and euphoria. The success of exercise in treating some forms of depression highlites the opiate systems role in the genesis of depression, I think.
Eric
Posted by SLS on August 12, 2015, at 6:51:12
In reply to Re: Has anyone tried high-dosed tianeptine? » SLS, posted by phidippus on August 12, 2015, at 6:49:57
This is the end of the thread.
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