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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by linkadge on July 6, 2010, at 17:01:34
I just read that nardil metabolizes to PEA. This is interesting. In essence taking Nardil is like taking an MAOI + PEA.
Linkadge
Posted by SLS on July 6, 2010, at 20:06:54
In reply to nardil metabolizes to PEA ?, posted by linkadge on July 6, 2010, at 17:01:34
Hi Linkadge.
> I just read that nardil metabolizes to PEA. This is interesting. In essence taking Nardil is like taking an MAOI + PEA.
Do you recall where you read that? That might possibly explain the "kick" I would get from Nardil immediately after taking a dose. Maybe the insomnia, too.
- Scott
Posted by angels78 on July 6, 2010, at 20:29:00
In reply to Re: nardil metabolizes to PEA ? » linkadge, posted by SLS on July 6, 2010, at 20:06:54
I <3 the peak plasma concentration from nardil.
Posted by jedi on July 7, 2010, at 1:01:38
In reply to Re: nardil metabolizes to PEA ? » linkadge, posted by SLS on July 6, 2010, at 20:06:54
> Hi Linkadge.
>
> > I just read that nardil metabolizes to PEA. This is interesting. In essence taking Nardil is like taking an MAOI + PEA.
>
> Do you recall where you read that? That might possibly explain the "kick" I would get from Nardil immediately after taking a dose. Maybe the insomnia, too.
>
>
> - Scott
Scott,
Here is one of many references which state that PEA is a metabolite of phenelzine.
Jedihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408023/pdf/jpn00088-0067.pdf
"Our interest in the trace amines was further stimulated by findings
in our laboratories and those of others that PEA is actually a
metabolite of phenelzine. Since phenelzine has been
shown in receptor binding studies and in behavioural
tests to produce down-regulation of fi-adrenergic receptors,
S"" we conducted further experiments, using a
behavioural response (change in locomotor activity) to
salbutamol, to examine the effects on P-adrenergic
activity of conditions that resulted in elevations of PEA.
These studies provided evidence that PEA may contribute
to the effects of phenelzine on P-adrenergic receptor function."
This is the end of the thread.
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