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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by Matthtew Duer on August 1, 2009, at 2:44:14
I'm looking for any of your thoughts on my situation as I've had some unusual reactions to meds and am puzzled as to how to proceed. I'm 27 and have been struggling with unrelenting depression for 17 years. My main problems are
*anhedonia
*apathy
*insomnia (can't get to sleep til 3 AM, sleep well, but can't get up and want to sleep all day)
*cognitive difficulties (psychomotor retardation)I've tried paxil, prozac, wellbutrin, effexor, neuronin, lithium, T3/T4, concerta, remron, zoloft, and lamictal.
Currently trying lexapro + 5mg deprenyl + 1g phenylalanine
My 1st AD was paxil and gave me complete remission at 2 weeks (maybe hypomania). Lasted for 4 days and pooped out. Dose upped twice, same thing happened twice. Later unsuccessfully tried wellbutrin. As I came off instead of experiencing withdraw I again had temporary remission which lasted about a week. Now whenever I take the slightest bit of wellbutrin I feel worse (especially cognitively) and experince a transient recovery as the drug leaves my system. Felt transiently better while comming off lamictal. Nothing else has made a diff. Can anyone make sense of these reactions or have experienced something similair themselves? Does anyone have a suggestion on what i should try?
Posted by morganpmiller on August 1, 2009, at 3:43:03
In reply to Need your input, posted by Matthtew Duer on August 1, 2009, at 2:44:14
How long are you trying these medications for? Are you giving them the 6 to 8 week recommended trial time? You only stop taking a medication in the first 2 to 4 weeks if it gives you unbearable side effects.
Posted by SLS on August 1, 2009, at 6:41:26
In reply to Need your input, posted by Matthtew Duer on August 1, 2009, at 2:44:14
> I'm looking for any of your thoughts on my situation as I've had some unusual reactions to meds and am puzzled as to how to proceed. I'm 27 and have been struggling with unrelenting depression for 17 years. My main problems are
>
> *anhedonia
> *apathy
> *insomnia (can't get to sleep til 3 AM, sleep well, but can't get up and want to sleep all day)
> *cognitive difficulties (psychomotor retardation)
>
> I've tried paxil, prozac, wellbutrin, effexor, neuronin, lithium, T3/T4, concerta, remron, zoloft, and lamictal.
>
> Currently trying lexapro + 5mg deprenyl + 1g phenylalanine
>
> My 1st AD was paxil and gave me complete remission at 2 weeks (maybe hypomania). Lasted for 4 days and pooped out. Dose upped twice, same thing happened twice. Later unsuccessfully tried wellbutrin. As I came off instead of experiencing withdraw I again had temporary remission which lasted about a week. Now whenever I take the slightest bit of wellbutrin I feel worse (especially cognitively) and experince a transient recovery as the drug leaves my system. Felt transiently better while comming off lamictal. Nothing else has made a diff. Can anyone make sense of these reactions or have experienced something similair themselves? Does anyone have a suggestion on what i should try?My case profile is similar to yours. This similarity includes 3-4 day remissions after chronic exposure (1-2 weeks) and discontinuation rebound improvements.
I am currently taking:
Parnate 80mg
nortriptyline 150mg
Lamictal 200mg
Abilify 20mg
lithium 450mg
Were you ever an ultra-rapid cycler?
- Scott
Posted by Phillipa on August 1, 2009, at 12:10:59
In reply to Re: Need your input, posted by SLS on August 1, 2009, at 6:41:26
Seriously? Not that I doubt you but when SSRI's out took for a few days no remission just horrible side effects and felt much better off them like phew that's over and then just low dose benzos so what does that make me as now the benzos just tire me no more energy from them. Phillipa
Posted by SLS on August 1, 2009, at 13:45:50
In reply to Re: Need your input » SLS, posted by Phillipa on August 1, 2009, at 12:10:59
> Seriously? Not that I doubt you but when SSRI's out took for a few days no remission just horrible side effects and felt much better off them like phew that's over and then just low dose benzos so what does that make me as now the benzos just tire me no more energy from them. Phillipa
Your concern is understandable. I'm really not sure what I would do if I were Matthew. I wouldn't let it go more than a few more days if nothing changes, though.
- Scott
Posted by SLS on August 1, 2009, at 13:50:08
In reply to Need your input, posted by Matthtew Duer on August 1, 2009, at 2:44:14
Please disregard my previous message. Phillipa's post confused me, and I thought I was responding to another thread.
Do you have any thoughts on what to do next?
- Scott
Posted by SLS on August 1, 2009, at 13:51:16
In reply to Re: Need your input » SLS, posted by Phillipa on August 1, 2009, at 12:10:59
> Seriously? Not that I doubt you but when SSRI's out took for a few days no remission just horrible side effects and felt much better off them like phew that's over and then just low dose benzos so what does that make me as now the benzos just tire me no more energy from them. Phillipa
I don't understand what you are referring to here.
- Scott
Posted by bulldog2 on August 1, 2009, at 14:03:03
In reply to Re: Need your input » SLS, posted by Phillipa on August 1, 2009, at 12:10:59
> Seriously? Not that I doubt you but when SSRI's out took for a few days no remission just horrible side effects and felt much better off them like phew that's over and then just low dose benzos so what does that make me as now the benzos just tire me no more energy from them. Phillipa
Do you suffer from some type of cognitive disorder? Sometimes your posts seem like a free flow of disordered and very disturbed thoughts from your subconcious. Have you ever brought this to the attention of your p-doc? I have no idea what you are trying to say.
To the poster. Please understand these are not typical reactions to psych meds. Phillipe has some unusal reactions to meds.
Posted by Sigismund on August 1, 2009, at 15:55:25
In reply to Need your input, posted by Matthtew Duer on August 1, 2009, at 2:44:14
Apart from getting you to sleep, Remeron sounds like a bad idea to me, especially for the day after. Concerta makes more sense. Since you were 10? Goodness.
Posted by Deputy 10derHeart on August 1, 2009, at 20:41:51
In reply to Re: Need your input, posted by bulldog2 on August 1, 2009, at 14:03:03
> Do you suffer from some type of cognitive disorder? Sometimes your posts seem like a free flow of disordered and very disturbed thoughts from your subconcious.
Please don't post anything that could lead others to feel accused or put down, and please be sensitive to their feelings.
You have been asked repeatedly not to post uncivil remarks directed at Phillipa, and also blocked for doing this last year. This could have been a 2-week block, but I chose a request to be civil, in case you'd like to reconsider and wish to apologize.
Dr. Bob encourages posters to apologize here; apologies can often contribute a lot to Babble's supportive atmosphere.
If you or others have questions about this or about posting policies in general, or are interested in alternative ways of expressing yourself, please see the FAQ:
http://www.dr-bob.org/babble/faq.html#civil
Follow-ups regarding these issues should be redirected to Psycho-Babble Administration. They, as well as replies to the above posts, should of course themselves be civil.
Dr. Bob is always free to override deputy decisions. His email is on the bottom of each page. Please feel free to email him if you believe this decision was made in error.
-- 10derHeart, acting as deputy to Dr. Bob
Posted by Phillipa on August 1, 2009, at 21:01:39
In reply to Please be civil » bulldog2, posted by Deputy 10derHeart on August 1, 2009, at 20:41:51
It's okay I see I basically hyjacked the thread my apologies to all involved especially the thread poster. Phillipa
Posted by Deputy 10derHeart on August 1, 2009, at 23:53:11
In reply to Re: Please be civil, posted by morganpmiller on August 1, 2009, at 22:32:21
Further discussion of administrative action on this thread has been moved to the Admin board.
Here's a link:
http://www.dr-bob.org/babble/admin/20090707/msgs/909779.html
Posted by Matthtew Duer on August 2, 2009, at 0:30:50
In reply to Need your input, posted by Matthtew Duer on August 1, 2009, at 2:44:14
SLS, are you a rapid cycler? I have no history of feeling "up" other than the bizarre medication responses. I know there is debate as to whether medication provoked mania or hypomania is actually a form of bipolar disorder. In any case I feel almost as if there may be a physical cause for my symptoms due to very early age of onset, duration and atypical responses to a variety of meds. I chased after CFS and Lyme for quite a while but those were dead ends. I am planning on trying magnesium and either ketoconazole or tramadol next. Leaning toward ketoconazole.
Posted by Meltingpot on August 2, 2009, at 13:56:43
In reply to Re: Need your input, posted by Matthtew Duer on August 2, 2009, at 0:30:50
Hi,
I think Phillipa was saying that it is possible to feel that bad on a drug so that when you come off it you feel such a relief and feel a bit better.
I personally used to get a rebound affect (in a good way) from stopping SSRIs. It doesn't seem to work anymore and I'm not bipolar.
Denise
Posted by Phillipa on August 2, 2009, at 18:32:23
In reply to Re: Need your input, posted by Meltingpot on August 2, 2009, at 13:56:43
Thank-you that is exactly what was trying to say. Love Phillipa
Posted by Phillipa on August 2, 2009, at 18:34:21
In reply to Re: Need your input, posted by Matthtew Duer on August 2, 2009, at 0:30:50
If you don't mind my asking what happened at the young age of l0. Thanks to Sigi for pointing out the young age. And you think it's more physical? Love Phillipa
This is the end of the thread.
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