Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by West on December 15, 2008, at 20:32:22
Just finished a week on these pills. Does anyone know if the cognitive difficulties subside? I am having trouble with concentration and memory in particular and feel pretty drowsy most of the time.
Posted by desolationrower on December 15, 2008, at 23:21:17
In reply to Cananyone help me out with Dosulepin aka Dothiepin, posted by West on December 15, 2008, at 20:32:22
why are you on that particular drug? There are other TCAs with less side effects. You can take a shorter half life antihistamine for sleep if you need. I think its popular with the NHS for some reason.
-d/r
Posted by West on December 16, 2008, at 11:54:22
In reply to Re: Cananyone help me out with Dosulepin aka Dothiepin, posted by desolationrower on December 15, 2008, at 23:21:17
> why are you on that particular drug? There are other TCAs with less side effects. You can take a shorter half life antihistamine for sleep if you need. I think its popular with the NHS for some reason.
>
> -d/rSaw a new GP who seemed to think it a good choice. I don't know what to think really, i don't feel good at all.
Posted by desolationrower on December 16, 2008, at 19:38:48
In reply to Re: Cananyone help me out with Dosulepin aka Dothiepin, posted by West on December 16, 2008, at 11:54:22
> > why are you on that particular drug? There are other TCAs with less side effects. You can take a shorter half life antihistamine for sleep if you need. I think its popular with the NHS for some reason.
> >
> > -d/r
>
> Saw a new GP who seemed to think it a good choice. I don't know what to think really, i don't feel good at all.
>
>Not sure what else you have tried, but i'd think an snri like milnacipran, duloxetine would have fewer side effects. Or, you could use a secondary tca like desipramine which has lower side effects than the dosulepin, and add a ssri if you condition does not remit. I sort of remember reading Doluepin has the least antimuscarininc sides of the dual-uptake TCAs, but with ssris and snris thats rather moot. I'd probably ask your doctor if you could switch to one of those options.
I think doctors end up using drugs they've used in the past to good effect. It sounds like the anticholinergic effect really hits you hard though.
-d/r
Posted by West on December 17, 2008, at 13:18:38
In reply to Re: Cananyone help me out with Dosulepin aka Dothiepin, posted by desolationrower on December 16, 2008, at 19:38:48
> > > why are you on that particular drug? There are other TCAs with less side effects. You can take a shorter half life antihistamine for sleep if you need. I think its popular with the NHS for some reason.
> > >
> > > -d/r
> >
> > Saw a new GP who seemed to think it a good choice. I don't know what to think really, i don't feel good at all.
> >
> >
>
> Not sure what else you have tried, but i'd think an snri like milnacipran, duloxetine would have fewer side effects. Or, you could use a secondary tca like desipramine which has lower side effects than the dosulepin, and add a ssri if you condition does not remit. I sort of remember reading Doluepin has the least antimuscarininc sides of the dual-uptake TCAs, but with ssris and snris thats rather moot. I'd probably ask your doctor if you could switch to one of those options.
>
> I think doctors end up using drugs they've used in the past to good effect. It sounds like the anticholinergic effect really hits you hard though.
>
> -d/rHi d/r
tried:
Fluoxetine
Escitalopram
Escitalopram w/bupropion
Moclobemide
Duloxetine
Tianeptine
MilnacipranBest was esc + bup which i took for stopping smoking.
I expect he has used it for years which is why he's putting me on it.
I was on modafinil + duloxetine ('weird and wonderful' combination) before but complained of insomnia which, ironically, is still going strong.
I suppose i have the bonus of being on an antihistamine and anticholinergic now too :(
W
Posted by desolationrower on December 17, 2008, at 14:56:10
In reply to Re: Cananyone help me out with Dosulepin aka Dothiepin, posted by West on December 17, 2008, at 13:18:38
How did you find the milnacipran? What went wrong with the escit&bupr combo?
If you have insomnia, i suppose that might be why doc suggested dosulepin. being sleepy all day isn't fun though.
-d/r
Posted by West on December 17, 2008, at 19:31:43
In reply to Re: Cananyone help me out with Dosulepin aka Dothiepin, posted by desolationrower on December 17, 2008, at 14:56:10
> How did you find the milnacipran? What went wrong with the escit&bupr combo?
>
> If you have insomnia, i suppose that might be why doc suggested dosulepin. being sleepy all day isn't fun though.
>
> -d/rI didn't take to milnacipran. Above 50mg it drove my heart rate through the roof. I was only taking zyban for smoking and was refused it by an NHS psych for depression. I think it was remission for those final 2-3 weeks, but still had insomnia.
I suppose i have to respect the new GP's wishes and will keep quiet for a few weeks until i've given the drug a proper run for it's money. It does get in the way though, this patriarchal power game of doctor over patient. I imagine they're much more inclined to listen when they're being paid privately.
Posted by Quintal on December 22, 2008, at 15:42:56
In reply to Cananyone help me out with Dosulepin aka Dothiepin, posted by West on December 15, 2008, at 20:32:22
I took it years ago for depression and insomnia. Reaction times and concentration were impaired the whole time I was taking it, but it was one of the more effective ADs I've taken. Hope it works out for you.
Q
This is the end of the thread.
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