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Dr. Bob is Robert Hsiung, MD,
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Posted by LostBoyinNCBecksDark on October 23, 2007, at 20:01:02
STAR*D discovered what many longtime depressives and other mood disordered people already knew...that present psychopharmacology is largely a joke. If you are looking to be restored to what you were before clinical depression, STAR*D says you have approximately a 50% chance if you rely upon psychopharmacology...thats not good odds.
ECT has a far better track record at treating clinical depression.
"J Clin Psychiatry. 2007;68 Suppl 10:8-10.
Limitations in efficacy of antidepressant monotherapy.
Rush AJ.
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9066, USA. john.rush@utsouthwestern.edu
Treatment for major depressive disorder does not achieve remission in about 50% of patients following 2 treatment trials. Researchers conducted the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study to compare various treatments for efficacy and tolerability. This article will focus on the efficacy of antidepressant monotherapy as determined by the STAR*D trial. Patients in the first treatment step of STAR*D received citalopram monotherapy and, depending on their response, moved either to follow-up or through a series of up to 4 additional treatment steps, each comprising different monotherapies, combinations, or augmentation treatment options. Only 1 of 3 patients remitted with the initial monotherapy. Rates of remission for each consecutive monotherapy were increasingly lower, suggesting that a series of monotherapy options may not be the best treatment strategy for patients who are nonresponsive to an initial monotherapy.
PMID: 17900203 [PubMed - in process]"
Eric
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