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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by river1924 on October 19, 2006, at 3:13:34
For about a week, risperidal seemed to make my thinking more organized. I had hoped it would reduce apathy and maybe let me get rid of some my other meds.
Instead, I became really short tempered and my ability to think and recall information was horrible.
I returned to my stelazine/razadyne combo. That works much better.
Have other people had this happen?
RiverJ.
Posted by ed_uk on October 19, 2006, at 14:21:19
In reply to Risperidone, posted by river1924 on October 19, 2006, at 3:13:34
Hi River,
Sorry to hear Risperdal didn't work out. Out of interest, what dose were you taking? ......and what dose of Stelazine do you take?
Ed
Posted by river1924 on October 19, 2006, at 23:36:03
In reply to Re: Risperidone » river1924, posted by ed_uk on October 19, 2006, at 14:21:19
Hi,
I only took .25 of risperidone. I take 2 mg of stelazine for a week and then take 1 mg. I must take razadyne with it.
River
Hope all's well.
> Hi River,
>
> Sorry to hear Risperdal didn't work out. Out of interest, what dose were you taking? ......and what dose of Stelazine do you take?
>
> Ed
Posted by ed_uk on October 20, 2006, at 14:23:25
In reply to Re: Risperidone » ed_uk, posted by river1924 on October 19, 2006, at 23:36:03
>I must take razadyne with it.
Why River?
Ed
PS. Razadyne sounds pretty scary. I'm relieved that it's still called Reminyl here!
Posted by river1924 on October 20, 2006, at 23:57:01
In reply to Re: Risperidone » river1924, posted by ed_uk on October 20, 2006, at 14:23:25
> >I must take razadyne with it.
Stelazine calms me but over several days, I feel like I have no thoughts at all. My memory is okay and I don't feel tired but my mind feels stuffed with cotton.
Razadyne lets me retain some imaginative vitality. I'm not sure why. Stelazine is an acetylcholine antagonist and Razadyne preserves acetylcholine. Razadyne may interfere with stelazine's more adverse effects which have something to do with that.
Stelazine is the only anti-psychotic I can tolerate because it isn't sedating. It causes more TD. Hopefully it is somewhat dose related because I only take one mg and I usually don't take it for months and months at a time. If it weren't for TD, I'd take it (with razadyne) all the time.
Stay in touch, River.
Posted by ed_uk on October 21, 2006, at 16:52:14
In reply to Re: Stelazine with a topping of razadyne » ed_uk, posted by river1924 on October 20, 2006, at 23:57:01
Hi River
Here is an advert for Stelazine from 1959.....
http://www.decodog.com/inven/MD/md30470.jpg
I thought you might be interested!
>Stelazine is an acetylcholine antagonist
Only a little, its antidopamine effect is probably why you feel like you have no thoughts.
>Stelazine is the only anti-psychotic I can tolerate because it isn't sedating.
Why APs have you tried?
Ed
Posted by river1924 on October 22, 2006, at 4:25:22
In reply to Re: Stelazine with a topping of razadyne » river1924, posted by ed_uk on October 21, 2006, at 16:52:14
Hey Ed,
Well, I can't say why it works.
Geodon: muscle spasms, sedating, depressive
Seroquel: gained 20 lbs in 2 weeks, very sedating, laughed almost too much/gave me a temper when it wore down after 10 or 12 hours
Zyprexa: very sedating, no positives
Abilify: not sedating but akathisia got worse and worse and nothing would reduce it, plus oddly enough (I've tried to take it several times) it makes me injure myself... the worst was when i tore the cartilage in my knee... it seems to destablize my joints
Loxitane (and its cousin Ascendin): These were the first drugs I was put on... I didn't know enough to just stop them. Now, I would have stopped after three days. Horrible nine months.
There have been others, perhaps. I can't think of any though.
I always think the newer AP's will work as well as the stelazine but they don't come close.
River.
Posted by ed_uk on October 22, 2006, at 7:13:24
In reply to Re: Stelazine with a topping of razadyne, posted by river1924 on October 22, 2006, at 4:25:22
Hi River
It would be very interesting to know how you would react to sulpiride or amisulpride. Flupentixol might also benefit, but with a higher risk of TD. Unfortunately, none of these drugs are marketed in the US.
Ed
Posted by river1924 on October 23, 2006, at 2:28:02
In reply to Re: Stelazine with a topping of razadyne » river1924, posted by ed_uk on October 22, 2006, at 7:13:24
Ed,
I'd be happy (and so would my liver and kidneys) if I could just reduce the crazy amount of meds I take.
clonazepam 4 mg qid
provigil 200 mg bid
dextroamphetamine ER 45 mg (in a day)
dextroamphetamine 15 mg in the evening
zoloft 25 mg
testosterone patch 5 mg+stelazine 1 mg
razadyne 4 mg tidCrazy! River.
Posted by ed_uk on October 24, 2006, at 16:10:28
In reply to Re: Stelazine with a topping of razadyne » ed_uk, posted by river1924 on October 23, 2006, at 2:28:02
Hi River
>clonazepam 4 mg qid
Do you mean qd (once daily)? Or do you really take 4mg four times a day? - some people do, but not many!
Ed
Posted by river1924 on October 25, 2006, at 0:06:19
In reply to Re: Stelazine with a topping of razadyne » river1924, posted by ed_uk on October 24, 2006, at 16:10:28
> Hi River
>
> >clonazepam 4 mg qid
>
> Do you mean qd (once daily)? Or do you really take 4mg four times a day? - some people do, but not many!
>
> Ed
>
I meant 1 mg qid (4 total mgs per day.) 16 mgs a day might make me a little sleepy...:) as it is, my eyes are dry dry dry and itchy because of it and the zoloft. R.
Posted by river1924 on October 28, 2006, at 19:20:31
In reply to Re: Stelazine with a topping of razadyne » river1924, posted by ed_uk on October 22, 2006, at 7:13:24
HI Ed, I ran across this article when I was trying to figure out something about epigenetics and it may (if I understand the lingo) explain some of the benefits I get from razadyne.
River.http://www.eurekah.com/chapter/1646
The nicotinic cholinergic system has been widely implicated in mediating learning and/or memory processes in human and nonhuman animals. This chapter highlights various areas of basic research in which stimulation or blockade of nicotinic acetylcholine receptors (nAChRs) has been shown to affect an animal’s performance in a variety of tasks thought to measure learning and memory. For example, under certain conditions, stimulation of nAChRs by nicotine (or other nAChRs agonists) can enhance working memory of primates as measured in a delayed matching-to-sample task. Attentional processes are also improved in rats as indexed by a five-choice serial reaction time task. Further, recent research suggests that stimulation of nAChRs by nicotine likely enhances the incentive salience of stimuli. We elaborate on a model by which this enhancement might occur and suggest that the role of this incentive mechanism in relation to learning and memory processes requires more empirical attention. Finally, there appears to be overlap in the processes by which nAChRs affect learning and memory. That is, enhanced incentive salience might be responsible for the increased attentional effects of nicotine, or vice versa. Subsequent research needs to refine the behavioral techniques so as better dissociate, if required, these mechanisms.
Posted by ed_uk on October 29, 2006, at 10:51:36
In reply to Re: Stelazine with a topping of razadyne, posted by river1924 on October 28, 2006, at 19:20:31
Hi River
Do you get any side effects from Razadyne?
Ed
Posted by river1924 on October 29, 2006, at 14:02:06
In reply to Re: Stelazine with a topping of razadyne » river1924, posted by ed_uk on October 29, 2006, at 10:51:36
Hello Ed,
Nope.
Exelon... a similiar med made me depressed.
R.
This is the end of the thread.
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