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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by flip-floppy on September 8, 2006, at 0:26:12
I have been diagnosed with delusional depression, but whenever I take anti-psychotics in therapeutic dosages, my condition gets worse. Is it possible that this is caused by the dopamine antagonistic properties of anti-psychotics? Or is it just a side-effect that will pass with time?
Posted by nellie7 on September 8, 2006, at 8:43:11
In reply to Antipsychotics causing WORSENING of symptoms?, posted by flip-floppy on September 8, 2006, at 0:26:12
Hi,
I have experienced the same effect of APs on delusional depression- a small amount added to an AD made me more depressed and more delusional.
I don't know why but it may have to do with antidopaminergic activity. It would be interesting to see if anyone on this board has any thoughts about this.Nellie.
Posted by flip-floppy on September 8, 2006, at 12:16:06
In reply to Re: Antipsychotics causing WORSENING of symptoms?, posted by nellie7 on September 8, 2006, at 8:43:11
Thanks! Have you found any medication that works for you, and if yes, which one?
Posted by nellie7 on September 9, 2006, at 16:48:20
In reply to Re: Antipsychotics causing WORSENING of symptoms? » nellie7, posted by flip-floppy on September 8, 2006, at 12:16:06
> Thanks! Have you found any medication that works for you, and if yes, which one?
I am on celexa 30 mg now and it helps a lot. I still have delusional tendencies but am not overwhelmed by the contents of the delusions and am also able to doubt their being real. I guess that for now not adding other meds would be the lesser of two evils.
Are you taking an anti-depressant? Are there any meds that do help you?
Take care,
Nellie.
Posted by flip-floppy on September 10, 2006, at 1:32:21
In reply to Re: Antipsychotics causing WORSENING of symptoms?, posted by nellie7 on September 9, 2006, at 16:48:20
Amisulpride helped me a great deal, but I had to discontinue it due to elevated prolactin levels. Now I'm on 100 mg Zoloft, and it seems to help so far. I will probably have to increase the dosage, though.
Posted by nellie7 on September 10, 2006, at 14:07:32
In reply to Re: Antipsychotics causing WORSENING of symptoms? » nellie7, posted by flip-floppy on September 10, 2006, at 1:32:21
Glad to hear the Zoloft is helping you. Do you find that this drug stops delusional thinking or just makes it more manageable?
Posted by flip-floppy on September 10, 2006, at 14:24:21
In reply to Re: Antipsychotics causing WORSENING of symptoms?, posted by nellie7 on September 10, 2006, at 14:07:32
More managable, but I hope increasing the dosage will help.
This is the end of the thread.
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