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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by cerebus on April 19, 2006, at 22:19:06
Has anyone tried Parnate but the side effects were too terrible, and were able to tolerate Nardil? That is the plan I am leaning toward. Any feedback would be deeply appreciated.
Posted by willyee on April 19, 2006, at 22:29:13
In reply to Failed Parnate, but found results Nardil., posted by cerebus on April 19, 2006, at 22:19:06
Total opposite,hopefully are two cases right here make it clear as cystal what we say over and over again,there is always an option,dont think one maoi is the other,better or worse,fail one,try the other,no different than u would other classes of meds.
Glad u found some relieaf on nardil.
Posted by MARTY on April 19, 2006, at 22:30:56
In reply to Failed Parnate, but found results Nardil., posted by cerebus on April 19, 2006, at 22:19:06
Hi Cerebus --Side effects are usually worst on Nardil than on Parnate. But it could depend on which type of side effects your more sensible. Give us the side effects that you had on Parnate so we can compare with Nardil.
Marty
> Has anyone tried Parnate but the side effects were too terrible, and were able to tolerate Nardil? That is the plan I am leaning toward. Any feedback would be deeply appreciated.
Posted by Phillipa on April 20, 2006, at 0:39:28
In reply to Re: Failed Parnate, but found results Nardil. » cerebus, posted by MARTY on April 19, 2006, at 22:30:56
Read my thread below this one. Please all answer I need lots of feedback. Love Phillipa
Posted by cerebus on April 20, 2006, at 7:56:58
In reply to Re: Failed Parnate, but found results Nardil. » MARTY, posted by Phillipa on April 20, 2006, at 0:39:28
I tried Parnate for 2 weeks. Side effects from this were horrible. Extreme GI disturbances were the main side effect: Constipation, Diarrhea, Cramping. Before I tried Parnate, I was cycling through alot of other medications trying to find the magic pill. I have been on Effexor for the past 2.5 years, just now coming off this to try Nardil. Was wondering if it was worth the time and effort. I have GAD, Social Phobia, probably Social Phobia worse. Thanks for all the support.
Posted by SLS on April 20, 2006, at 8:07:39
In reply to Re: Failed Parnate, but found results Nardil., posted by cerebus on April 20, 2006, at 7:56:58
> Was wondering if it was worth the time and effort.
Simply put, there are people who respond to Nardil who do not respond to Parnate.
Regarding side effects, I found Nardil to produce more hypotension, delayed micturition, and anorgasmia as compared to Parnate. These seem to get better the longer you are on the drug.
On paper, Nardil looks like a more effective drug for you than does Effexor. I guess you have to decide whether or not it is worth the gamble. What would you lose if Nardil proves ineffective?
- Scott
Posted by naughtypuppy on April 20, 2006, at 9:34:44
In reply to Re: Failed Parnate, but found results Nardil., posted by cerebus on April 20, 2006, at 7:56:58
> I tried Parnate for 2 weeks. Side effects from this were horrible. Extreme GI disturbances were the main side effect: Constipation, Diarrhea, Cramping. Before I tried Parnate, I was cycling through alot of other medications trying to find the magic pill. I have been on Effexor for the past 2.5 years, just now coming off this to try Nardil. Was wondering if it was worth the time and effort. I have GAD, Social Phobia, probably Social Phobia worse. Thanks for all the support.
I havent't tried Nardil yet, but when I first tried Parnate I hade explosive diarrhea for about 3 weeks, then it went away with minimal remaining side effects. Maybe if you continued a bit longer the GI problems would have went away.
Posted by Crazy Horse on April 20, 2006, at 10:24:50
In reply to Re: Failed Parnate, but found results Nardil. » cerebus, posted by naughtypuppy on April 20, 2006, at 9:34:44
> > I tried Parnate for 2 weeks. Side effects from this were horrible. Extreme GI disturbances were the main side effect: Constipation, Diarrhea, Cramping. Before I tried Parnate, I was cycling through alot of other medications trying to find the magic pill. I have been on Effexor for the past 2.5 years, just now coming off this to try Nardil. Was wondering if it was worth the time and effort. I have GAD, Social Phobia, probably Social Phobia worse. Thanks for all the support.
>
> I havent't tried Nardil yet, but when I first tried Parnate I hade explosive diarrhea for about 3 weeks, then it went away with minimal remaining side effects. Maybe if you continued a bit longer the GI problems would have went away.
>I agree with Naughtypuppy. I find the longer i'm on Parnate the less side-effects i have. Sometimes we have to *wait out* some adverse side effects of meds, as they sometimes dissapear, and then all that's left is the beneficial properties of the med. My pdoc calls it pushing through..I find more often than not it worksfor me. :)
Good Luck,
-Crazy Horse
Posted by jedi on April 24, 2006, at 2:20:07
In reply to Re: Failed Parnate, but found results Nardil., posted by cerebus on April 20, 2006, at 7:56:58
Hi,
IMHO a combination of Nardil with clonazepam is about as good as it gets for knocking out social anxiety. Nardil is also the Gold standard for atypical depression. As always "your mileage may vary". But, for treatment resistant atypical depression with social anxiety, you won't see much better results than Nardil with clonazepam.
Good luck,
JediPS Parnate did nothing for me; we are all so different.
> I tried Parnate for 2 weeks. Side effects from this were horrible. Extreme GI disturbances were the main side effect: Constipation, Diarrhea, Cramping. Before I tried Parnate, I was cycling through alot of other medications trying to find the magic pill. I have been on Effexor for the past 2.5 years, just now coming off this to try Nardil. Was wondering if it was worth the time and effort. I have GAD, Social Phobia, probably Social Phobia worse. Thanks for all the support.
Posted by Crazy Horse on April 24, 2006, at 5:53:55
In reply to Re: Failed Parnate, but found results Nardil. » cerebus, posted by jedi on April 24, 2006, at 2:20:07
> Hi,
> IMHO a combination of Nardil with clonazepam is about as good as it gets for knocking out social anxiety. Nardil is also the Gold standard for atypical depression. As always "your mileage may vary". But, for treatment resistant atypical depression with social anxiety, you won't see much better results than Nardil with clonazepam.
> Good luck,
> Jedi
>
> PS Parnate did nothing for me; we are all so different.
This is true, we are all different. I also have atypical depression and social phobia, Nardil didn't help me at all, but Parnate sure has. Just have to try them to see what works best for you. But, a 2wk. trial is not long enough, unfortunately 4-6, sometimes 8 wks are needed for a therapeutic response.
Crazy Horse
Posted by Caedmon on April 24, 2006, at 7:37:54
In reply to Re: Failed Parnate, but found results Nardil. » cerebus, posted by jedi on April 24, 2006, at 2:20:07
>> IMHO a combination of Nardil with clonazepam is about as good as it gets for knocking out social anxiety. Nardil is also the Gold standard for atypical depression. As always "your mileage may vary". But, for treatment resistant atypical depression with social anxiety, you won't see much better results than Nardil with clonazepam.>>
If I have, or am prone to, depression I might want to use a different benzodiazepine. Clonazepam can be so depressogenic, it certainly is for me. (Not for everyone.)
Also I've never seen any studies that compared Nardil vs. other MAOIs for atypical depression although I can't say I've really looked either. So, one might work better than the other, Nardil isn't necessarily better in this regard.
That's my understanding anyway!
- C
Posted by Crazy Horse on April 24, 2006, at 8:40:53
In reply to Re: Failed Parnate, but found results Nardil. » jedi, posted by Caedmon on April 24, 2006, at 7:37:54
> >> IMHO a combination of Nardil with clonazepam is about as good as it gets for knocking out social anxiety. Nardil is also the Gold standard for atypical depression. As always "your mileage may vary". But, for treatment resistant atypical depression with social anxiety, you won't see much better results than Nardil with clonazepam.>>
>
> If I have, or am prone to, depression I might want to use a different benzodiazepine. Clonazepam can be so depressogenic, it certainly is for me. (Not for everyone.)
>
> Also I've never seen any studies that compared Nardil vs. other MAOIs for atypical depression although I can't say I've really looked either. So, one might work better than the other, Nardil isn't necessarily better in this regard.
>
> That's my understanding anyway!
>
> - CHave you ever tried Xanax (benzodiazapine) ? It's supposed to be excellent for social phobia and anxiety in general, and it supposedly has some antidepressant properties as well. It is short acting, similar to ativan.
CH
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