Psycho-Babble Medication Thread 633604

Shown: posts 1 to 14 of 14. This is the beginning of the thread.

 

Parnate without Insomnia..is it possible???

Posted by Crazy Horse on April 15, 2006, at 18:49:34

I'm really getting frustrated with this parnate induced insomnia...mentally i feel really good, but i'm too tired to do anything. In other words, the insomnia is messin' up the good thing i got going here with parnate. Why does it always have to be something??!

Has anyone here been on parnate 60mgs. daily or more and not had trouble with insomnia. If so, advice would be very much appreciated.

Here's the thing for me. Benzo's, lunesta and ambien do not work for me. So my pdoc has me on Trazodone 150-200 mgs. at bedtime. The traz was working great for about a month but lately not so great, about every 3rd night i don't sleep at all, not a wink! That day, my day is wasted as you can guess.

I'm really frustrated, any advice would be nice. Thanks.

-Crazy Horse...going crazy without sleep!

 

Re: Parnate without Insomnia..is it possible???

Posted by SLS on April 15, 2006, at 19:47:47

In reply to Parnate without Insomnia..is it possible???, posted by Crazy Horse on April 15, 2006, at 18:49:34

> I'm really getting frustrated with this parnate induced insomnia...mentally i feel really good, but i'm too tired to do anything. In other words, the insomnia is messin' up the good thing i got going here with parnate. Why does it always have to be something??!
>
> Has anyone here been on parnate 60mgs. daily or more and not had trouble with insomnia. If so, advice would be very much appreciated.
>
> Here's the thing for me. Benzo's, lunesta and ambien do not work for me. So my pdoc has me on Trazodone 150-200 mgs. at bedtime. The traz was working great for about a month but lately not so great, about every 3rd night i don't sleep at all, not a wink! That day, my day is wasted as you can guess.
>
> I'm really frustrated, any advice would be nice. Thanks.
>
> -Crazy Horse...going crazy without sleep!


I once combined Parnate 60mg + desipramine 150mg. I couldn't sleep at all. My doctor decided to put me on a combination of Halcion + Ativan. It worked great. Halcion is the most potent benzodiazepine and will put almost anyone to sleep. The only problem is that it has an extremely short half-life. People often experience rebound awakenings during night. Taking Ativan helped to prevent this from happening because it has a longer half-life. So, Halcion puts you to sleep and Ativan (or Restoril) keeps you asleep.

I didn't like chloral hydrate, but it might be worth a try.

You may end up having to look at Seroquel 25-50mg.


- Scott

 

Re: Parnate without Insomnia..is it possible??? » SLS

Posted by Crazy Horse on April 15, 2006, at 20:34:04

In reply to Re: Parnate without Insomnia..is it possible???, posted by SLS on April 15, 2006, at 19:47:47

Thanks Scott, I'll talk to my pdoc about these drugs...man i need something!

-Crazy Horse

 

Re: Parnate without Insomnia..is it possible??? » Crazy Horse

Posted by MARTY on April 15, 2006, at 21:10:35

In reply to Re: Parnate without Insomnia..is it possible??? » SLS, posted by Crazy Horse on April 15, 2006, at 20:34:04


Chloral hydrate works for me. Seroquel was VERY effective, but the cholinergic effect isn't as hard on everyone. And lately I tried LYRICA which is the new Neurontin (It's as identic as the black and white are identic) It put me to sleep well.

Marty


> Thanks Scott, I'll talk to my pdoc about these drugs...man i need something!
>
> -Crazy Horse

 

Re: Parnate without Insomnia..is it possible??? » MARTY

Posted by Phillipa on April 15, 2006, at 22:42:27

In reply to Re: Parnate without Insomnia..is it possible??? » Crazy Horse, posted by MARTY on April 15, 2006, at 21:10:35

chloral hydrate is wonderful for sleep but don't know if it would go with an MAOI and no alcohol at all it is then a Mickey Finn. Fondly Phillipa

 

Re: Parnate without Insomnia..is it possible??? » Phillipa

Posted by MARTY on April 16, 2006, at 0:48:10

In reply to Re: Parnate without Insomnia..is it possible??? » MARTY, posted by Phillipa on April 15, 2006, at 22:42:27


Hi Phillipa!

Hmmm.. I was taking it with Nardil without problem. My Pdoc and pharmacist both told me it was compatible. But about alchool and Chloral hydrate, that's a good question! I drink very rarely so I never had the chance to try.


Marty


> chloral hydrate is wonderful for sleep but don't know if it would go with an MAOI and no alcohol at all it is then a Mickey Finn. Fondly Phillipa

 

Re: Parnate without Insomnia..is it possible???

Posted by blueberry on April 16, 2006, at 14:34:08

In reply to Parnate without Insomnia..is it possible???, posted by Crazy Horse on April 15, 2006, at 18:49:34

I doubt anything that is anti-histimine, like trazodone or remeron or tricyclic is going to help for long. And if the benzos haven't helped, then maybe take SLS's suggestion of specific ones and at whatever dose does the job. Other than that, I think the only way is to temporarily block the dopamine receptors and the 5ht2 receptors, which means antipsychotic. Zyprexa or seroquel. In my own experience, and in just viewing posts here, zyprexa seems to keep its sedating qualities for a very long time, whereas seroquel's often wears off requiring higher doses.

 

Re: Parnate without Insomnia..is it possible???

Posted by Caedmon on April 17, 2006, at 17:47:56

In reply to Re: Parnate without Insomnia..is it possible???, posted by blueberry on April 16, 2006, at 14:34:08

The single most sedating drug I've ever taken is Mysoline (primidone). It metabolizes into phenobarbital. That stuff *will* work, only problem is that it makes me so stupid and dizzy that it's not worth it. But maybe you'd tolerate phenobarbital better.

I'm on Parnate now to 20mg, no insomnia. <shrug> I'm waiting for the 'amphetamine-like properties' of this stupid drug to kick in, because I need it.

- C

 

Re: Parnate without Insomnia..is it possible??? » Caedmon

Posted by Crazy Horse on April 17, 2006, at 18:22:44

In reply to Re: Parnate without Insomnia..is it possible???, posted by Caedmon on April 17, 2006, at 17:47:56

> The single most sedating drug I've ever taken is Mysoline (primidone). It metabolizes into phenobarbital. That stuff *will* work, only problem is that it makes me so stupid and dizzy that it's not worth it. But maybe you'd tolerate phenobarbital better.
>
> I'm on Parnate now to 20mg, no insomnia. <shrug> I'm waiting for the 'amphetamine-like properties' of this stupid drug to kick in, because I need it.
>
> - C

Oh it will C, but not at 20 mgs. How long you been on it? I was at 60mgs. when it kicked in for me and man did it feel good. It still feels good 2.5 mos. later. Let me know how long you've been on 20...I was at 60mgs. by day 10.

-Crazy Horse

 

Re: Parnate without Insomnia..is it possible???

Posted by Caedmon on April 18, 2006, at 3:39:53

In reply to Re: Parnate without Insomnia..is it possible??? » Caedmon, posted by Crazy Horse on April 17, 2006, at 18:22:44

Not even a week, I'm just ~barely~ starting this drug. Thanks for the encouragement. I am probably going to need that higher dose too.

- C

 

Re: Parnate without Insomnia..is it possible??? » Caedmon

Posted by Crazy Horse on April 18, 2006, at 9:50:13

In reply to Re: Parnate without Insomnia..is it possible???, posted by Caedmon on April 18, 2006, at 3:39:53

> Not even a week, I'm just ~barely~ starting this drug. Thanks for the encouragement. I am probably going to need that higher dose too.
>
> - C

Still at 20 after one week? What does your pdoc have planned, has he talked about a high dose at all? Do you take all of your dose when you awaken?

Let me know, and i'll send you back some ideas that have worked for me.

-CH

 

Re: Parnate without Insomnia..is it possible???

Posted by Caedmon on April 18, 2006, at 19:31:33

In reply to Re: Parnate without Insomnia..is it possible??? » Caedmon, posted by Crazy Horse on April 18, 2006, at 9:50:13

> > Not even a week, I'm just ~barely~ starting this drug. Thanks for the encouragement. I am probably going to need that higher dose too.
> >
> > - C
>
> Still at 20 after one week? What does your pdoc have planned, has he talked about a high dose at all? Do you take all of your dose when you awaken?
>
> Let me know, and i'll send you back some ideas that have worked for me.
>
> -CH

Hi. He said 10 mg for 2 days, then 20mg for a week. Then 30 mg for the remaining 4 weeks until my followup. Right now I'm taking the 20mg in split doses (10 in the morning, 10 at about lunchtime).

- C

 

Re: Parnate without Insomnia..is it possible??? » Caedmon

Posted by Crazy Horse on April 19, 2006, at 9:34:25

In reply to Re: Parnate without Insomnia..is it possible???, posted by Caedmon on April 18, 2006, at 19:31:33






> Hi. He said 10 mg for 2 days, then 20mg for a week. Then 30 mg for the remaining 4 weeks until my followup. Right now I'm taking the 20mg in split doses (10 in the morning, 10 at about lunchtime).
>
> - C

Hi C,
First off listen to your pdoc, not me. :) These are just my thoughts and opinions. Is your Doc pretty familiar with maoi's? Is he/she generally pretty conservative? Don't get me wrong it's good to be safe, but if you don't get a reaction at 30, that's a long time to wait(1 month). Some people do get a good reaction at 30, and are able to stay there for a long time. For me, I needed sixty to get a reaction with Parnate. My pdoc gives me a lot of freedom because he knows me well (25yrs.) so I was on 60 by day 8 or 9 and it kicked in for me on day 10. Been working great ever since but i have had to increase dose to 150,(plan to stay at this dose). I have always needed high doses of everything to treat my TR Depression. For me, I took my full dose of parnate all in the morning until i got to 100, now i spread it out. Usually 80-90 am, 50 at noon, and 20 between 2:00 and 3:00. This works great for me. Hey good Luck, and feel free to contact me with questions anytime. May Parnate Power be with you! :)

Monte

 

Re: Parnate without Insomnia..is it possible??? » Crazy Horse

Posted by Caedmon on April 19, 2006, at 22:20:41

In reply to Re: Parnate without Insomnia..is it possible??? » Caedmon, posted by Crazy Horse on April 19, 2006, at 9:34:25

> > Hi. He said 10 mg for 2 days, then 20mg for a week. Then 30 mg for the remaining 4 weeks until my followup. Right now I'm taking the 20mg in split doses (10 in the morning, 10 at about lunchtime).
> >
> > - C
>
>if you don't get a reaction at 30, that's a long time to wait(1 month).>>

Yeah my doc is pretty conservative. The latency has been my worry too. I will probably evaluate it like he told me to up to 3 weeks and hang in there the last week if I'm feeling a difference. If I have had no improvements, go up to 40mg the last week by myself.

- C


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