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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by fires on April 24, 2005, at 12:44:24
I've been struggling to keep from sinking into a major dep.. I have been having more spells of mild anhedonia. Woke up not so good, then watched TV and read some of the ads in the Sunday paper. Started feeling myself sliding downhill -- interest dropping .
At almost exactly 08:50, I went over the edge -- anhedonia >> significant psychomotor retardation (suddenly) >> extreme fatigue.Anyone else experiences these sudden spells? Maybe I"ll rebound later today -- or maybe I'm stuck until a med kicks in.
Question: I'm on 300 mg Wellbutrin. Can I be "switched" directly to Effexor, while I decrease Wellbutrin and increase Effexor? (Drop Well. to 150 mg and add Effexor 37.5 mg NOW).
I feel extremely sick and tired. Any thoughts and/or ideas welcome. If I don't get back to reply, I've probably not rebounded at all.
Thanks.
Posted by Ritch on April 24, 2005, at 14:36:17
In reply to suddenly over the edge, posted by fires on April 24, 2005, at 12:44:24
> I've been struggling to keep from sinking into a major dep.. I have been having more spells of mild anhedonia. Woke up not so good, then watched TV and read some of the ads in the Sunday paper. Started feeling myself sliding downhill -- interest dropping .
> At almost exactly 08:50, I went over the edge -- anhedonia >> significant psychomotor retardation (suddenly) >> extreme fatigue.
>
> Anyone else experiences these sudden spells? Maybe I"ll rebound later today -- or maybe I'm stuck until a med kicks in.
>
> Question: I'm on 300 mg Wellbutrin. Can I be "switched" directly to Effexor, while I decrease Wellbutrin and increase Effexor? (Drop Well. to 150 mg and add Effexor 37.5 mg NOW).
>
> I feel extremely sick and tired. Any thoughts and/or ideas welcome. If I don't get back to reply, I've probably not rebounded at all.
>
> Thanks.I would *add* 37.5 of Effexor to your current WB. I've pitched all my other antidepressants, but I've kept a stash of these two just in case I experience what you are experiencing. WB and Effexor are the only two AD's (esp. in combo) that have much punch for me to snap me out it. I've had "attacks" of lethargy before that are sudden. I can't go to sleep though.. it is like I'm real agitated, but my body becomes like a block of lead and I can't move...
Posted by fires on April 24, 2005, at 16:30:00
In reply to Re: suddenly over the edge » fires, posted by Ritch on April 24, 2005, at 14:36:17
> > I've been struggling to keep from sinking into a major dep.. I have been having more spells of mild anhedonia. Woke up not so good, then watched TV and read some of the ads in the Sunday paper. Started feeling myself sliding downhill -- interest dropping .
> > At almost exactly 08:50, I went over the edge -- anhedonia >> significant psychomotor retardation (suddenly) >> extreme fatigue.
> >
> > Anyone else experiences these sudden spells? Maybe I"ll rebound later today -- or maybe I'm stuck until a med kicks in.
> >
> > Question: I'm on 300 mg Wellbutrin. Can I be "switched" directly to Effexor, while I decrease Wellbutrin and increase Effexor? (Drop Well. to 150 mg and add Effexor 37.5 mg NOW).
> >
> > I feel extremely sick and tired. Any thoughts and/or ideas welcome. If I don't get back to reply, I've probably not rebounded at all.
> >
> > Thanks.
>
> I would *add* 37.5 of Effexor to your current WB. I've pitched all my other antidepressants, but I've kept a stash of these two just in case I experience what you are experiencing. WB and Effexor are the only two AD's (esp. in combo) that have much punch for me to snap me out it. I've had "attacks" of lethargy before that are sudden. I can't go to sleep though.. it is like I'm real agitated, but my body becomes like a block of lead and I can't move..._________________________________________________
Thanks,My dep. let up some in a couple of hours (thank God!), but then I was extraordinarily tired -- yet not able to sleep-- at first. I did fall asleep for a while. I ate lunch and I'm now experiencing a repeat of the severe tiredness. Maybe I'll sleep again. This is quite weird.
I see my pdoc Tues., and I'm hoping she will agree to the 37.5 mg of Effexor -- since it and Parnate are the only 2 meds that have pulled me from severe dep..
Thanks
Posted by fires on April 25, 2005, at 10:54:21
A follow up to this thread:
http://www.dr-bob.org/babble/20050423/msgs/488780.htmlI'm not kidding. I inadvertently discovered that Pepto Bismol has helped my situation tremendously. I have no clue what GI problem can "mess" by brain up so fast and severely.
Any thoughts?
Thanks
Posted by Phillipa on April 25, 2005, at 17:55:12
In reply to Over the edge (cont.), posted by fires on April 25, 2005, at 10:54:21
What? Are you saying that you took Pepto Bismol and your depression went away? Fondly, Phillipa
Posted by fires on April 25, 2005, at 18:26:53
In reply to Re: Over the edge (cont.) » fires, posted by Phillipa on April 25, 2005, at 17:55:12
> What? Are you saying that you took Pepto Bismol and your depression went away? Fondly, Phillipa
My acute, severe dep. with anhedonia "went away".
I'm still very tired, and of course not better overall than before my recent "attack". My theory is that I have/had some kind of intestinal "thing" that was affecting my brain.
When I was on Parnate for 14+ years, I would experience "near depression" when I would get a flu or cold.
Support for my idea:
http://www.biopsychiatry.com/cytokine-abnorm.htmOf course there are many other possible explanations -- buy I will never be convinced that it was a placebo response- never.
This is the end of the thread.
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