![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by NealP on October 27, 2004, at 6:38:29
I've remained well on reboxetine (Edronax, a selective NRI) since January 2002. Over the past month I've experienced "breakthrough" depression, which is distressing after being well for so relatively long. I had also been on carbamazepine but decided to come off in April because it caused slight nausea and diziness and I'd never been manic. I did seem to miss some of its sedative effects with slightly more disturbed sleep before crashing in September.
As I've been on a number of different kinds of antidepressant in the past, especially during my last depressive episode, I've just been started on
pindolol (a beta blocker) as augmentation, rather than switching antidepressant.I'd be interested to hear from others with experience of long-term reboxetine treatment and/or augmentation with pindolol.
(I think reboxetine has not yet been licensed in the US?)
Posted by Bill LL on October 27, 2004, at 9:07:35
In reply to relapse on long-term reboxetine, posted by NealP on October 27, 2004, at 6:38:29
Ususally when an antidepressant works for a long time, and then becomes less effective, a dose increase is all that is needed. But I guess you or your doc had a reason not to do that.
> I've remained well on reboxetine (Edronax, a selective NRI) since January 2002. Over the past month I've experienced "breakthrough" depression, which is distressing after being well for so relatively long. I had also been on carbamazepine but decided to come off in April because it caused slight nausea and diziness and I'd never been manic. I did seem to miss some of its sedative effects with slightly more disturbed sleep before crashing in September.
>
> As I've been on a number of different kinds of antidepressant in the past, especially during my last depressive episode, I've just been started on
> pindolol (a beta blocker) as augmentation, rather than switching antidepressant.
>
> I'd be interested to hear from others with experience of long-term reboxetine treatment and/or augmentation with pindolol.
>
> (I think reboxetine has not yet been licensed in the US?)
Posted by NealP on October 27, 2004, at 16:25:42
In reply to Re: relapse on long-term reboxetine, posted by Bill LL on October 27, 2004, at 9:07:35
What happened is that when I initially crashed we upped the dose of reboxetine from the standard 8mg to maximum 12mg - I bounced back up after 2 or 3 days but then crashed again a couple of weeks later and things have stayed the same since. Taking the dose any higher would be going off licence and I don't seem to be getting any benefit from the drug in any case. I'm just hoping the augmentation may get it working again!
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.