Psycho-Babble Medication Thread 388990

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norepinephrine and sedatation

Posted by flmm on September 9, 2004, at 21:51:55

Is it possible for a norepinephrine heavy drug to be somewhat sedating? Just curious as it seems to stimulate in most forms.

 

Re: norepinephrine and sedatation

Posted by King Vultan on September 10, 2004, at 7:46:27

In reply to norepinephrine and sedatation, posted by flmm on September 9, 2004, at 21:51:55

> Is it possible for a norepinephrine heavy drug to be somewhat sedating? Just curious as it seems to stimulate in most forms.


I found both nortriptyline and Strattera to be sedating myself, and they are both norepinephrine selective reuptake inhibitors. However, so are both desipramine and protriptyline, and I found neither of them to be sedating. Obviously, there must be additional effects at work beyond the issue of blocking norepinephrine reuptake.

Todd


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