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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by KaraS on August 15, 2004, at 18:15:22
You wrote in a post from the archives:
"Niacinamide down-regulates histamine synthesis, and also blocks mast-cell degranulation (histamine release). It also, coincidentally, is an agonist at GABA receptors."
How much niacinamide should one take to prevent allergic responses (such as cholinergic urticaria)? I'm currently taking 150 mg. of it in my multiple and B-complex with no other niacin, which I'm assuming isn't very much.
Would the dosage you're recommending make me too mellow or relaxed due to the GABAergic activity? (I'm already far to mellow).
There's more that you've written about niacinamide since you got back from vacation but I can't seem to find it... so I don't remember if this is all that I wanted to ask you about it. Do you remember who you replied to about this or what you said so I can find that post? You've only been back a day - don't know why I can't find it. If not, I'm sure the issue will surface again in the future.
Kara
Posted by Larry Hoover on August 15, 2004, at 20:08:47
In reply to Niacinamide and allergic response - Larry, posted by KaraS on August 15, 2004, at 18:15:22
> You wrote in a post from the archives:
>
> "Niacinamide down-regulates histamine synthesis, and also blocks mast-cell degranulation (histamine release). It also, coincidentally, is an agonist at GABA receptors."
>
> How much niacinamide should one take to prevent allergic responses (such as cholinergic urticaria)? I'm currently taking 150 mg. of it in my multiple and B-complex with no other niacin, which I'm assuming isn't very much.No, you could take much more than that. I'd set the upper limit at around 2,000 mg/day.
> Would the dosage you're recommending make me too mellow or relaxed due to the GABAergic activity? (I'm already far to mellow).
It might make you more mellow, but maybe that's the West Coast thingie?
> There's more that you've written about niacinamide since you got back from vacation but I can't seem to find it... so I don't remember if this is all that I wanted to ask you about it. Do you remember who you replied to about this or what you said so I can find that post? You've only been back a day - don't know why I can't find it. If not, I'm sure the issue will surface again in the future.
>
> KaraI posted a lot of posts over on the Larry board, errr, alternative board. I don't recall which one it was that mentioned niacinamide.
Lar
Posted by KaraS on August 15, 2004, at 22:04:25
In reply to Re: Niacinamide and allergic response - Larry » KaraS, posted by Larry Hoover on August 15, 2004, at 20:08:47
> > You wrote in a post from the archives:
> >
> > "Niacinamide down-regulates histamine synthesis, and also blocks mast-cell degranulation (histamine release). It also, coincidentally, is an agonist at GABA receptors."
> >
> > How much niacinamide should one take to prevent allergic responses (such as cholinergic urticaria)? I'm currently taking 150 mg. of it in my multiple and B-complex with no other niacin, which I'm assuming isn't very much.
>
> No, you could take much more than that. I'd set the upper limit at around 2,000 mg/day.
>
> > Would the dosage you're recommending make me too mellow or relaxed due to the GABAergic activity? (I'm already far to mellow).
>
> It might make you more mellow, but maybe that's the West Coast thingie?
>
> > There's more that you've written about niacinamide since you got back from vacation but I can't seem to find it... so I don't remember if this is all that I wanted to ask you about it. Do you remember who you replied to about this or what you said so I can find that post? You've only been back a day - don't know why I can't find it. If not, I'm sure the issue will surface again in the future.
> >
> > Kara
>
> I posted a lot of posts over on the Larry board, errr, alternative board. I don't recall which one it was that mentioned niacinamide.
>
> Lar
Thanks. I meant to post this on the "Larry board". I just forgot where I was. (My, aren't we getting a big head since we got back from vacation?)-K
This is the end of the thread.
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