Psycho-Babble Medication Thread 333191

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Q to Ame: DXM(60mg) for amphetamine tolerance?

Posted by btnd on April 6, 2004, at 1:10:10

Hi Ame! Hope you're doing well..
Just wanted to ask you a question - do you know of any scientific studies/abstracts showing that DXM (at 60mg/day) works as a NDMA antagonist? Id appreciate your input.

Take care.

Personal regime (SP+dysthymia+add)
1.clonazepam 2mg
2.ghb/xyrem 3x/daily
3.adderall

 

Re: Q to Ame: DXM(60mg) for amphetamine tolerance?

Posted by Ame Sans Vie on April 6, 2004, at 8:14:34

In reply to Q to Ame: DXM(60mg) for amphetamine tolerance?, posted by btnd on April 6, 2004, at 1:10:10

Hiya,

I wasn't able to look through all these studies to see if they gave any definitive information on human dosages of DXM which block NMDA receptors, but 60mg Delsym seems to work great for me -- there's no way in hell I'd still be finding relief from 60mg Adderall if it weren't for the DXM!

~Dextromethorphan Potentiates the Antinociceptive Effects of Morphine and the delta-Opioid Agonist SNC80 in Squirrel Monkeys

http://jpet.aspetjournals.org/cgi/content/full/300/2/435

~Clinically Available NMDA Receptor Antagonists Memantine and Dextromethorphan Reverse Existing Tolerance to the Antinociceptive Effects of Morphine in Mice

http://opioids.com/nmda/memantine.html

~The Uses and Psychoactive Properties of Dextromethorphan

http://sulcus.berkeley.edu/mcb/165_001/papers/manuscripts/_67.html

~MorphiDex (MS:DM) Double-Blind, Multiple-Dose Studies in Chronic Pain Patients

http://opioids.com/morphidex/

I'll try to find some more info, and if you have any other questions -- feel free! :-)

 

Thanks Ame! DXM(60mg) for amph tolerance? (nm) » Ame Sans Vie

Posted by btnd on April 7, 2004, at 19:58:21

In reply to Re: Q to Ame: DXM(60mg) for amphetamine tolerance?, posted by Ame Sans Vie on April 6, 2004, at 8:14:34

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