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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by matthhhh on August 9, 2003, at 14:33:03
Why do the ssris cause sooo much fatigue to sooo many people. Serotonin is supposed to boost your mood and fatigue is contrary to that.
Exstacy increases the supply of serotonin in the brain, it makes you feel good without ANY sedation. Why is this? I mean cant they make serotonin meds that increase the serotonin and make you feel good without the sedation?
Posted by crazychickuk on August 9, 2003, at 14:49:17
In reply to SSRIS and fatigue, posted by matthhhh on August 9, 2003, at 14:33:03
some type of extasy makes u sedated too....
Posted by jlo820 on August 9, 2003, at 17:25:56
In reply to SSRIS and fatigue, posted by matthhhh on August 9, 2003, at 14:33:03
>>> Serotonin is supposed to boost your mood and fatigue is contrary to that.
I don't know the anser to your question, but the above statement is not really true.
Posted by Janelle on August 10, 2003, at 15:51:50
In reply to SSRIS and fatigue, posted by matthhhh on August 9, 2003, at 14:33:03
I have been told that there are MANY different Serotonin receptors in the brain, hence why one a-d works for one person and not another (person A might need to hit certain Serotonin receptors that let's say Prozac acts on, while Person B might need to hit other Serotonin receptors that let's say Paxil but not Prozac acts on) -- at least this is how it was explained to me.
What I'm getting at is that the SSRI's may be hitting receptors that are also involved in fatigue whereas if Ecstasy also hits Serotonin receptors (I know NOTHING about this), it may be hitting ones that are not involved in fatigue; perhaps there are even Serotonin receptors that are involved in activity or whatever the opposite of fatigue would be! Just my humble opinion/guess.
Posted by matthhhh on August 10, 2003, at 19:40:39
In reply to Re: SSRIS and fatigue » matthhhh, posted by Janelle on August 10, 2003, at 15:51:50
hey janelle i completely agree with you, i think that exstacy promote different serotonin circuits that promote activity. I dont know why they cant make ssris do the same.
Posted by Bill L on August 11, 2003, at 9:16:18
In reply to SSRIS and fatigue, posted by matthhhh on August 9, 2003, at 14:33:03
You might want to try one or more of the 3 things that worked for me to fight SSRI fatigue:
1) I take the SSRI at night (8 pm or later)
2) I take powdered whey in the morning for breakfast- mixed with water (high protein, low glycemic value)
3) I eat an ounce of dark (not milk) chocolate early each day (possible benefits include lower blood pressure, lower LDL, and fights tooth decay)each of the above 3 has helped me to combat SSRI fatigue
Another solution is to supplement with Wellbutrin.
Posted by matthhhh on August 11, 2003, at 10:54:28
In reply to Re: SSRIS and fatigue, posted by Bill L on August 11, 2003, at 9:16:18
hi there, thanks for the reply. but ive tried all these things, sedation is just sooo powerful. Anyone benefit off lexapro?
Posted by Susan J on August 11, 2003, at 12:26:07
In reply to Re: SSRIS and fatigue, posted by matthhhh on August 11, 2003, at 10:54:28
Hi,
I just wanted to empathize with the sedating effects of SSRI's. I was on Paxil for a year and it was debilitating! When I first went on it, I slept 16 hours a day, easily. I struggled to lead a normal life. I was able to, but felt miserable.
So. I quit Paxil without my doc's approval (I weaned myself, but still had some side effects), and went on Wellbutrin alone. I'm in my fourth week and I think it's working for me. I totally lost ANY sedating effect, have all my old energy back, and feel wonderful....just waiting to make sure depression doesn't come back.
Also, I've read that ecstacy use actually damages serotonin receptors by releasing HUGE amounts of serotonin (overload) and that ecstacy users could end up permanently depressed, even after stopping ecstacy use....
This is the end of the thread.
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