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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by crazychickuk on February 25, 2003, at 10:58:28
This site i went to is the most interesting site ever all about seritone etc, go to the second one down, it explains that anxiety and depression are caused by to LITTLE seratone, and most ssris just block the seritone and sometimes that is why they can cause anxiety or even worse things,as you have to little seratone in the first place for it to be blocked,, i beleive this, as i get alot of anxiety when i tried any ssri.. (which is alot) i obviousley dont have enough seratone being released, so i need a med that releases it such as 5-HTP.. (tryptophan)
and did you also know that effexor isnt actually an ssri it is more like a tricylic, interesting isnt it? we dont get told nothing and there arnt any tests that i know off to actually measure the seritone in our system, docs just give u an ssri to block the seritone (block depression, anxiety etc) and it isnt sorting the actuall problem out in some people as there course is to little seritone in the first place..
Posted by beardedlady on February 25, 2003, at 11:24:37
In reply to very interesting, posted by crazychickuk on February 25, 2003, at 10:58:28
SSRIs block the reuptake, or recycling of seratonin transmitters. It's difficult to understand, but it has something to do with keeping those receptors working. You only have a limited number of them, so making them start over again would be foolish. They just float around free so you can use them all the time.
Yeah, it doesn't even make sense to me, but maybe someone who's scientific can explain it better.
The bottom line is that it doesn't keep your brain from manufacturing seratonin.
The following came from the site you linked:
6. HOW SSRI ANTIDEPRESSANTS PROBABLY WORKIf too little serotonin (or noradrenaline) produces the symptoms of depression then correcting this should help to reduce the symptoms. One way of doing this is to block the reuptake (recycling) of transmitters. This is just what an SSRI antidepressant does. They block the reuptake of serotonin, so the next time an impulse comes along, there is more transmitter, a stronger message is passed, and activity in that part of the brain is increased.
Posted by crazychickuk on February 25, 2003, at 15:11:53
In reply to maybe you misunderstood... » crazychickuk, posted by beardedlady on February 25, 2003, at 11:24:37
what i tried to explain is that, some people with anxiety/depression dont have enough serotone in the first place so taking ssri's to block what u do have is wrong .. as that isnt the prob... i should know as none have worked for me.
Posted by Ame Sans Vie on February 25, 2003, at 15:53:23
In reply to Re: maybe you misunderstood..., posted by crazychickuk on February 25, 2003, at 15:11:53
Hi there... maybe I can explain this (I'll try anyway :-)
First of all, I'm sure you know serotonin is a messenger chemical in the brain; it's responsible for carrying nerve impulses across synapses in the brain. Normally, when serotonin "jumps" the synapse, not all of it is accepted at the other side-- thus it gets sent back across the synapse to whence it came. This is called "reuptake". This is what beardedlady meant by "recycling" of serotonin.
When an SSRI (selective serotonin reuptake *inhibitor*) is being taken, the serotonin sent back from across the synapse is blocked from re-entering the nerve terminal it came from. Therefore it's forced to travel back across the synapse. This all results in higher levels of the neurotransmitter being available throughout the brain.
I'm no expert on this, so anyone correct me if I'm wrong about the terminology.
Posted by stjames on February 25, 2003, at 18:58:17
In reply to Re: maybe you misunderstood..., posted by crazychickuk on February 25, 2003, at 15:11:53
None of this has anything to do with too much aor too little 5HT. It is about regulation.
Posted by rayww on February 26, 2003, at 16:47:33
In reply to very interesting, posted by crazychickuk on February 25, 2003, at 10:58:28
I thought it was a very interesting article. It certainly raised some questions about drugs in general. Have these medications ever been compared to illegal drugs, and if so, what are the similarities?
Posted by David Smith on February 27, 2003, at 22:18:18
In reply to Re: very interesting » crazychickuk, posted by rayww on February 26, 2003, at 16:47:33
> I thought it was a very interesting article. It certainly raised some questions about drugs in general. Have these medications ever been compared to illegal drugs, and if so, what are the similarities?
Funny you should mention that.
I just started on risperdal (with Neurontin)
and it fells like I have smoked a joint
(at least I am assuming that's what it would feel
like if I had ever smoked a joint).
;-)
Posted by David Smith on March 2, 2003, at 2:48:58
In reply to Re: very interesting, posted by David Smith on February 27, 2003, at 22:18:18
> > I thought it was a very interesting article. It certainly raised some questions about drugs in general. Have these medications ever been compared to illegal drugs, and if so, what are the similarities?
--------------------------------------------------------
> Funny you should mention that.
> I just started on risperdal (with Neurontin)
> and it fells like I have smoked a joint
> (at least I am assuming that's what it would feel
> like if I had ever smoked a joint).
> ;-)
>------------------------------------------------------
It seems that coffee was the initiating factor
for the effect. Hmmmm. I think I better keep track
of my food intake!
This is the end of the thread.
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