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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by LizDorothea on August 1, 2002, at 14:55:48
Hi,
Quick question, which was all ready stated in the subject:
Does Parnate (or Nardil) have any anti-psychotic properties? If they don't, are there are any anti-psychotics that you can take if you take MAOIs? In particular, what about Seroquel?
Thank you so much!
Liz
Posted by turalizz on August 1, 2002, at 15:55:10
In reply to Do Parnate/Nardil have anti-psychotic properties?, posted by LizDorothea on August 1, 2002, at 14:55:48
> Hi,
> Quick question, which was all ready stated in the subject:
> Does Parnate (or Nardil) have any anti-psychotic properties? If they don't, are there are any anti-psychotics that you can take if you take MAOIs? In particular, what about Seroquel?
> Thank you so much!
> LizNo they don't.
Why would you combine an antipsychotic that blocks dopamine and several other receptors together with a MAOI? Doesn't make any sense to me.If you are feeling psychotic on a particular MAOI, then something that antagonises 5-HT2 receptors would be a much better idea than an antipsychotic I think. Remeron is not a good idea to combine with a MAOI, but maybe trazodone or mianserin would be OK if you can tolerate the sadation.
(Shawn could give you much information about it.)cem
Posted by cybercafe on August 2, 2002, at 2:44:06
In reply to Do Parnate/Nardil have anti-psychotic properties?, posted by LizDorothea on August 1, 2002, at 14:55:48
> Does Parnate (or Nardil) have any anti-psychotic properties? If they don't, are there are any anti-psychotics that you can take if you take MAOIs? In particular, what about Seroquel?
no I don't think they have antipsychotic properties
yes you can definately take an antipsychotic with them -- i believe risperdal is a popular choice
Posted by Ritch on August 2, 2002, at 10:07:27
In reply to Do Parnate/Nardil have anti-psychotic properties?, posted by LizDorothea on August 1, 2002, at 14:55:48
> Hi,
> Quick question, which was all ready stated in the subject:
> Does Parnate (or Nardil) have any anti-psychotic properties? If they don't, are there are any anti-psychotics that you can take if you take MAOIs? In particular, what about Seroquel?
> Thank you so much!
> Liz
Liz,It depends on what monograph you read! Go to www.mentalhealth.com and click on Medications and then Tranylcypromine (or Parnate). It mentions use "in psychotic depressive states" such as manic-depression, involutional melancholia, etc. The Canadian monograph is different.
Mitch
Posted by LizDorothea on August 3, 2002, at 3:37:20
In reply to Re: Do Parnate/Nardil have anti-psychotic properties?, posted by turalizz on August 1, 2002, at 15:55:10
> > Hi,
> > Quick question, which was all ready stated in the subject:
> > Does Parnate (or Nardil) have any anti-psychotic properties? If they don't, are there are any anti-psychotics that you can take if you take MAOIs? In particular, what about Seroquel?
> > Thank you so much!
> > Liz
>
> No they don't.
> Why would you combine an antipsychotic that blocks dopamine and several other receptors together with a MAOI? Doesn't make any sense to me.
>
> If you are feeling psychotic on a particular MAOI, then something that antagonises 5-HT2 receptors would be a much better idea than an antipsychotic I think. Remeron is not a good idea to combine with a MAOI, but maybe trazodone or mianserin would be OK if you can tolerate the sadation.
> (Shawn could give you much information about it.)
>
> cem
>
>
My brother seems to be suffering from atypical depression and has not received much relief from SSRIs, tricyclics, or other ADs. I take Parnate and am doing well on it (after having tried lots of combinations of meds), so we thought maybe my brother should try it too. The thing is, he is hearing voices which I never did, so he might be needing something anti psychotic in addition to an anti depressant.
We don't know if we should even start him on an MAOI since it would take about 2 weeks before he could try something else if it doens't work for him. However, if it has anti-psychotic properties and/or can be combined with and anti-psychotic then that's another story. Sorry I am rambling, I am really sleepy.
Thanks again,
Liz
Posted by cybercafe on August 3, 2002, at 6:11:31
In reply to Re: Do Parnate/Nardil have anti-psychotic properties? » turalizz, posted by LizDorothea on August 3, 2002, at 3:37:20
> We don't know if we should even start him on an MAOI since it would take about 2 weeks before he could try something else if it doens't work for him. However, if it has anti-psychotic properties and/or can be combined with and anti-psychotic then that's another story. Sorry I am rambling, I am really sleepy.
i would probably go with whatever the doctor says... but i do know that the newer atypical antipsychotics have antidepressant effects... so it might be a good idea (or it might not) to see how well the antipsychotic works on the depression and then choose an antidepressant afterward ...
this is something you can think about anyways...
Posted by missliz on August 4, 2002, at 2:45:21
In reply to Re: Do Parnate/Nardil have anti-psychotic properties? » turalizz, posted by cybercafe on August 3, 2002, at 6:11:31
Yes. For me they did, and they were great. But here's your problem- Zyprexa is the one that's supposedly anti depressant, but you can't use it with MAOIs as it's a brain scrambling combination. Straight from the mouth of my psychopharmacologist, the famous expert on MAOIs (snicker). But I believe him on this- I got the graphic details on some other patients on this combination. Bad news. Risperdol is the only one safe with MAOIs. Or you could just use Haldol. Novels aren't always that much better drugs, just have shinier ad campaigns.
But whats the dx? I'm assuming major depression with psychotic features? The MAOI alone would eventually fix it up, but even with an AP can he avoid suicide by Dominoes double pepperoni during the run up period?? One of the criteria for MAOI use is being with it enough to follow the diet. The stuff takes time to work. Are you doing this inpatient?
Don't get me wrong- I'm a huge fan of these drugs and have found them to be incredibly stabilizing in my case, real wonder drugs. I'm bipolar II and need less mood stabilizer on them. It takes six to eight weeks for the full rewiring to happen though- and it's a rough time. You need to ask the doc about the practicalities of getting there from here.
This is the end of the thread.
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