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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Denise528 on June 21, 2002, at 15:16:01
Hi IsoM,
Can you tell me how long it takes for Adrafinil to work and at what doseage? , I know that you swear by it.
A while back I took 1 x 300mg tab, at the time the ADs that I was on were making me extremely agitated and distressed so I took an Adrafinil hoping to get an instant hit. I didn't and I then worried that it might have made the situation worse so didn't take one again.
I'm now a little bit more stable (if a bit zombiefied) on Effexor, the depression has not lifted and I'm thinking of giving the Adrafinil a proper go. How long roughly does it take to work, at what doseage (bearing in mind that I can drink 10 cups of coffee a day without feeling stimulated and do not have ADD) and is it ok to take it with Effexor and Lamictal?Thanks.....Denise
Thanks
Posted by IsoM on June 21, 2002, at 21:29:02
In reply to Adrafinil - IsoM or other users, posted by Denise528 on June 21, 2002, at 15:16:01
Oh, yes, I do swear by it. I only wish everyone else got the same benefits as I do on it.
It took a full week before I noticed anything - & then it was only that I was less sleepy (the narcolepsy thing). Bit by bit as time went on, I felt better. Two weeks, I was pretty well awake during the day without feeling drowsy any more. Noticed that I was feeling more general well-being. Three weeks, I was feeling a real contentment & like I'd found my brains again. Not nearly as forgetful, easier to keep track of small things that previously felt scrambled, & such.
I ran out of adrafinil twice. This last time I started up again, I wondered if the effect had worn off - two weeks & I didn't feel that much better. But I've been taking it for a good two months now & I really feel good. A gentle, all-over contentment & bursts of real joy & enthusiasm as the moment dictates. I feel bright, alert, awake, energetic & still have my normal hyperness of my ADHD but not the frsutrations & addleness of it. It also seems to have an AD effect for me, but that's what I read is normal about adrafinil.
Just because you can take lots of caffeine I'm not sure says much. I can take caffeine tablets (when I don't have adrafinil) & sleep on them easily. I can sleep through Dexedrine too, if I want to. I found that initially, two 300 mg tablets daily worked good. But I think some of it was the PEA effect with natural dopamine kicking in. I take three 300 mg tablets daily. Occasionally, I forget the second dose or I'm not home to take it. It doesn't matter if I miss the occasional tablet - no problem.
You've got to remember that there's many who insist they've felt differences immediately. I certainly don't want to discount their thoughts - they've obviously felt something - but I'm not sure it's due to the adrafinil in all users. The literature on adrafinil does say it takes a week or more before anything is noticed. Benefits are said to increase for a continuing 2-3 months.
I've noticed no untoward side-effects, whatsoever! Zilch - zippo! Which is wonderful - it doesn't even interfere with my sleep. From a previous night when I hadn't enough sleep & a hard day's work, I can take an afternoon nap too, if I so wish. Wonderful stuff for me!
Unfortuantely, I know nothing of what it does with the drugs you've mentioned. Why not ask a pharmacist how modafinil would go with them - very similar to its cousin, adrafinil?
Posted by Denise528 on June 22, 2002, at 6:47:26
In reply to Re: Adrafinil - IsoM or other users » Denise528, posted by IsoM on June 21, 2002, at 21:29:02
> Oh, yes, I do swear by it. I only wish everyone else got the same benefits as I do on it.
>
> It took a full week before I noticed anything - & then it was only that I was less sleepy (the narcolepsy thing). Bit by bit as time went on, I felt better. Two weeks, I was pretty well awake during the day without feeling drowsy any more. Noticed that I was feeling more general well-being. Three weeks, I was feeling a real contentment & like I'd found my brains again. Not nearly as forgetful, easier to keep track of small things that previously felt scrambled, & such.
>
> I ran out of adrafinil twice. This last time I started up again, I wondered if the effect had worn off - two weeks & I didn't feel that much better. But I've been taking it for a good two months now & I really feel good. A gentle, all-over contentment & bursts of real joy & enthusiasm as the moment dictates. I feel bright, alert, awake, energetic & still have my normal hyperness of my ADHD but not the frsutrations & addleness of it. It also seems to have an AD effect for me, but that's what I read is normal about adrafinil.
>
> Just because you can take lots of caffeine I'm not sure says much. I can take caffeine tablets (when I don't have adrafinil) & sleep on them easily. I can sleep through Dexedrine too, if I want to. I found that initially, two 300 mg tablets daily worked good. But I think some of it was the PEA effect with natural dopamine kicking in. I take three 300 mg tablets daily. Occasionally, I forget the second dose or I'm not home to take it. It doesn't matter if I miss the occasional tablet - no problem.
>
> You've got to remember that there's many who insist they've felt differences immediately. I certainly don't want to discount their thoughts - they've obviously felt something - but I'm not sure it's due to the adrafinil in all users. The literature on adrafinil does say it takes a week or more before anything is noticed. Benefits are said to increase for a continuing 2-3 months.
>
> I've noticed no untoward side-effects, whatsoever! Zilch - zippo! Which is wonderful - it doesn't even interfere with my sleep. From a previous night when I hadn't enough sleep & a hard day's work, I can take an afternoon nap too, if I so wish. Wonderful stuff for me!
>
> Unfortuantely, I know nothing of what it does with the drugs you've mentioned. Why not ask a pharmacist how modafinil would go with them - very similar to its cousin, adrafinil?
Hello,Thanks for that advice, I'm definately not getting any horrible side effects from them so I'll continue to take them and just imagine they are vitamin pills, I have almost a whole pack so I may as well there's nothing to lose. I'll just try not to expect anything and then I won't be disappointed if they don't work. If they do work I'll let you know.
Denise
Posted by IsoM on June 23, 2002, at 21:36:18
In reply to Re: Adrafinil - IsoM or other users, posted by Denise528 on June 22, 2002, at 6:47:26
Denise, your attitude is a good one to take about meds - "I'll just try not to expect anything and then I won't be disappointed if they don't work." It's how I feel. I'm very cynical about medications & supplements. There's either so much false marketing hype with supplements, or for meds, something can have such varied reactions in different people. So I never 'expect' something to work.
Seriously, I fully expect it NOT to work instead, so if I do start feeling better, I don't even attribute it to what I'm taking initially. I'll look for all sorts of other reasons for the improvement as to often we forget that small events or weather can make us feel temporarily better.
Then when I continue to feel good or get even better over a period of weeks, I'll finally think whatever it is actually may work. This way I can always discount any placebo effect. I try to take a very objective view of my condition to rationally judge what works best.
What strength are you taking though? If the dose is too low & you would normally need a larger dose, you may not feel much different & simply assume it doesn't work when, in actuality, it might. I felt nothing at one 300 mg tablet a day. Two made me feel better but I was still quite sleepy, & while happier, not realy content. Three is just right for me.
Posted by Denise528 on June 25, 2002, at 15:22:23
In reply to Re: Adrafinil - real benefits or placebo effect » Denise528, posted by IsoM on June 23, 2002, at 21:36:18
Hello again,
Are you are taking 3 x 300mg? I'm only taking 1 x 300mg a day as I haven't got that many tablets to last me. Doestn't that cost you a lot of money? I think I only got about 30 x 300mg tablets at the cost of about £20.00. How much does the Adrafinil cost you a month?
I think it's safe for me to take the Adrafinil with Lactimal, I've checked previous threads and other people seem to be taking it with Dexedrine so hopefully I'll be ok.
Denise
Posted by IsoM on June 25, 2002, at 17:57:41
In reply to Re: Adrafinil - real benefits or placebo effect » Denise528, posted by Denise528 on June 25, 2002, at 15:22:23
Yes, Denise three tablets a day at 300 mg each so a total of 900 mg per day. Not really cheap but cheaper than what you pay. I get one box of 40 tablets for about $32, Canadian. It should be about £14 for you equivalent. I order larger amounts at one time to keep shipping & handling charges low. I go through a little more than two boxes a month = $70 per month. I figure people will often spend that much in a month of buying coffee, snacks, & junk food and/or restaurants which I don't do. I balance one cost against another & opt for what really counts for me.
It's just that it enables me to do so much & while I'm not happy paying that much, I don't need to pay for any of my other meds. My union covers the costs.
This is the end of the thread.
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