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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by borderliner21 on January 26, 2002, at 19:16:52
Does zyprexa make dystonia worse? I am going to be taking a neuroleptic soon. Should I go with clozapine or zyprexa? Which one is least likely to affect my dystonia?
Posted by OldSchool on January 26, 2002, at 19:47:12
In reply to dystonia and neuroleptics, posted by borderliner21 on January 26, 2002, at 19:16:52
> Does zyprexa make dystonia worse? I am going to be taking a neuroleptic soon. Should I go with clozapine or zyprexa? Which one is least likely to affect my dystonia?
Yes Zyprexa could exacerbate dystonia. Clozapine is supposed to have the least chance of causing movement disorders, although the chance is not zero. Clozapine has the fewest movement disorder side effects, but more than makes up for this in other side effects. You have to have your blood drawn once a week with clozapine.
Posted by jimmygold70 on January 28, 2002, at 12:43:33
In reply to dystonia and neuroleptics, posted by borderliner21 on January 26, 2002, at 19:16:52
Clozapine, Olanzapine, Quetiapine and Sertindole does not cause EPS in usual doses. Clozapine and Sertindole are the safest in respect to EPS. However, Clozapine is associated with Agranulocytosis, something you don't want to get (deadly!). So, I would recommend on Zyprexa (olanzapine) if you are not concerned with weight gain and somnolence, Quetiapine for if you do, and if you really don't want any weight gain go for Geodon (Ziprasidone), although it is associated with some EPS.
(Source: Synopsis of psychiatry, Kaplan & Sadock, 1998)Jimmy
> Does zyprexa make dystonia worse? I am going to be taking a neuroleptic soon. Should I go with clozapine or zyprexa? Which one is least likely to affect my dystonia?
Posted by OldSchool on January 28, 2002, at 15:18:15
In reply to Re: dystonia and neuroleptics » borderliner21, posted by jimmygold70 on January 28, 2002, at 12:43:33
> Clozapine, Olanzapine, Quetiapine and Sertindole does not cause EPS in usual doses.
The above is untrue. I personally am testament to this. I suffered a bothersome case of EPS from just 50 mg of Seroquel this past fall. Atypical anti-psychotics can and do cause EPS. Its a myth Atypicals never cause EPS.
Clozapine is supposed to be the only atypical which supposedly "never" causes EPS.
Old School
This is the end of the thread.
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