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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by PaintItBlack on July 30, 2001, at 17:15:27
I've tried about a zillion antidepressants. I have nothing to show but side effects.
My doctor and I are talking about what to try next. What with building up to megadoses, augmenting, it's a big commitment of time and energy. But if something works...
Effexor and Parnate are two meds that I haven't given serious trials. I'm curious to hear from anyone who has tried both, and comparisons. Thanks.
Painting It Black
Posted by SalArmy4me on July 30, 2001, at 22:26:13
In reply to Effexor Or Parnate? AD # 23, posted by PaintItBlack on July 30, 2001, at 17:15:27
Idea: Parnate (tranylcypromine) + Risperidone
Stoll, Andrew L. MD 1,2. Haura, Gail MA 1. Tranylcypromine Plus Risperidone for Treatment-Refractory Major Depression. Journal of Clinical Psychopharmacology. 20(4):495-496, August 2000:
"All five of the nonpsychotic depressed outpatients in this trial had treatment-refractory and prolonged unipolar or bipolar depression and responded to the combination of tranylcypromine plus risperidone. Four of five patients experienced a dramatic and sustained antidepressant response to the combination. Despite the lack of psychosis and previous MAOI monotherapy (in four of five patients) that was less than successful, these patients responded to the combination of tranylcypromine and risperidone. Further studies are required to determine whether the risperidone alone or the combination of tranylcypromine and risperidone was responsible for the antidepressant effects observed in these patients. All patients, except for one who experienced overwhelming sedation, tolerated the medications well. Although not necessarily causal, the tranylcypromine and risperidone were started simultaneously in the three patients with the most dramatic responses..."
Helpful Links:
http://biopsychiatry.com/trandep.htm
http://www.preskorn.com/cgi-bin/sp.pl?words=tranylcypromine&wt=be&bl=an&d=/books/omd_s7.html
http://www.dr-bob.org/tips/split/MAOIs-in-high-doses-and-wi.html
This is the end of the thread.
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