Psycho-Babble Medication Thread 61558

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parnate

Posted by dean on May 3, 2001, at 19:09:28

I started taking parnate two weeks ago and the side effects (fatigue, weakness) are difficult to tolerate.
Do the side effects subside? So far no effect on depression. I'm told that 50-60 mg are needed for relief. Any thoughts welcomed. Dean

 

Re: parnate

Posted by SalArmy4me on May 4, 2001, at 1:18:31

In reply to parnate, posted by dean on May 3, 2001, at 19:09:28

You might ask your doctor about adding a prescription wakefulness medication: http://www.dr-bob.org/tips/split/MAOIs-in-high-doses-and-wi.html

> I started taking parnate two weeks ago and the side effects (fatigue, weakness) are difficult to tolerate.
> Do the side effects subside? So far no effect on depression. I'm told that 50-60 mg are needed for relief. Any thoughts welcomed. Dean

 

Re: parnate

Posted by missliz on May 6, 2001, at 1:20:35

In reply to parnate, posted by dean on May 3, 2001, at 19:09:28

> I started taking parnate two weeks ago and the side effects (fatigue, weakness) are difficult to tolerate.
> Do the side effects subside? So far no effect on depression. I'm told that 50-60 mg are needed for relief. Any thoughts welcomed. Dean

I used Parnate and later Nardil for years and they are both excellent drugs- It took a month for the Parnate to kick in but one day I woke up in a whole new world!
Are you sure the fatigue and weakness are the Parnate and not the depression? Parnate is usually used for very serious illness, since the dietary restrictions are pretty demanding and can be tough to live with. Talk to your doc and make sure you haven't just started to notice symptoms of the depression because you're feeling a little better. My understanding is that if you notice how crummy you feel you're getting well, whether from depression or any thing else.
My experience of MAOI's was truly profound; my life changed drasticly for the better and I hope you'll get the same benefit. You just may have to lay low a little longer while it works its magic. Keep an eye on your blood pressure and be VERY CAREFUL with your diet. I never actually had much trouble, but a few M&Ms here and raisins there- it can stack up in your system and make you just miserable drooling sick. You'll learn quick.
The quality of life MAOIs gave me was totally worth the trouble. Keep us posted.
missliz

 

Re: parnate

Posted by Michael K on May 6, 2001, at 21:41:16

In reply to Re: parnate, posted by missliz on May 6, 2001, at 1:20:35

> > I started taking parnate two weeks ago and the side effects (fatigue, weakness) are difficult to tolerate.
> > Do the side effects subside? So far no effect on depression. I'm told that 50-60 mg are needed for relief. Any thoughts welcomed. Dean

Dean,

I have taken Parnate on and off (mostly on) for 12 years. I have never found fatigue and weakness to be a side effect. On the contrary, Parnate is generally quite energizing for most people. The only significant side effects I have experienced are low libido and sensitivity to cold weather. Unfortunately, I believe it is starting to poop out for me. I started on 40 mg and now take 80mg, but it's not cutting it. However, back in 1988, it saved me when nothing else worked. Good luck.
>
> I used Parnate and later Nardil for years and they are both excellent drugs- It took a month for the Parnate to kick in but one day I woke up in a whole new world!
> Are you sure the fatigue and weakness are the Parnate and not the depression? Parnate is usually used for very serious illness, since the dietary restrictions are pretty demanding and can be tough to live with. Talk to your doc and make sure you haven't just started to notice symptoms of the depression because you're feeling a little better. My understanding is that if you notice how crummy you feel you're getting well, whether from depression or any thing else.
> My experience of MAOI's was truly profound; my life changed drasticly for the better and I hope you'll get the same benefit. You just may have to lay low a little longer while it works its magic. Keep an eye on your blood pressure and be VERY CAREFUL with your diet. I never actually had much trouble, but a few M&Ms here and raisins there- it can stack up in your system and make you just miserable drooling sick. You'll learn quick.
> The quality of life MAOIs gave me was totally worth the trouble. Keep us posted.
> missliz

 

Re: parnate

Posted by JahL on May 6, 2001, at 22:22:32

In reply to parnate, posted by dean on May 3, 2001, at 19:09:28

> I started taking parnate two weeks ago and the side effects (fatigue, weakness) are difficult to tolerate.
> Do the side effects subside? So far no effect on depression. I'm told that 50-60 mg are needed for relief. Any thoughts welcomed. Dean

Parnate is the only drug I haven't been able to reach the max rec'd dose on. Strangely, for a drug that's supposed to be slightly energizing (I think it has amphetamine metabolites), anything above 25mg wld knock me cold. Literally. Maybe it says something about my messed-up brain chemistry. I persisted for 4 or 5 wks but nothing changed. Nardil wasn't nearly so sedating. However it was like being on an LSD come-down (whatever that is :)). I found that the side-effects of neither drug dissapated with time. (High-dose Moclobemide had almost no side-effects.)

However I guess it's a case of different strokes 4 different folks; MAOIs are excellent drugs for some people & the dietary restrictions are a small price to pay for yr mental well-being.

No real way of knowing if *yr* side-effects will subside...but if they get worse as you increase the dose, it may be worth considering an alternative MAOI. Just my opinion.

J.


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