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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by matze on February 19, 2001, at 12:48:36
Hi,
I take sulpiride/200mg for dysthymia/social phobia. I`m satisfied with it but I experience sexual dysfunction with it ( i`m male). Is prolactin the cause and can dopamine agonists like pergolide, pramipexole or bromocriptin help? Is such a combination useful at all (dopamine antagonist + dopamine agonist)?
Thanks for help
Posted by AndrewB on February 19, 2001, at 14:11:01
In reply to sulpiride , posted by matze on February 19, 2001, at 12:48:36
> Hi,
> I take sulpiride/200mg for dysthymia/social phobia. I`m satisfied with it but I experience sexual dysfunction with it ( i`m male). Is prolactin the cause and can dopamine agonists like pergolide, pramipexole or bromocriptin help? Is such a combination useful at all (dopamine antagonist + dopamine agonist)?
> Thanks for helpGood questions. Elevated prolacitin is the cause of your problems. Bromocriptine has been documented to normalize prolactin levels elevated by sulpiride thus taking away the associated side effects. It does not interefere with the action of sulpiride. Pramipexole is also prolactin lowering and won't interfere with the action of sulpiride but I haven't heard of anyone using the combo. I tried amisulpride (cousin of sulpiride) with pramipexole but I didn't experience increased mood, motivation or anything except the best jumpshot I've ever had in my life! Anyway, there is the possibility that the combo of Mirapex and sulpiride will provide additional mood benefit while normalizing your prolactin levels.
BTW, be sure you are using the lowest effective dosage of sulpiride to minimize side effects.
AndrewB
Posted by matze on February 20, 2001, at 8:28:13
In reply to Re: sulpiride , posted by AndrewB on February 19, 2001, at 14:11:01
> > Hi,
> > I take sulpiride/200mg for dysthymia/social phobia. I`m satisfied with it but I experience sexual dysfunction with it ( i`m male). Is prolactin the cause and can dopamine agonists like pergolide, pramipexole or bromocriptin help? Is such a combination useful at all (dopamine antagonist + dopamine agonist)?
> > Thanks for help
>
> Good questions. Elevated prolacitin is the cause of your problems. Bromocriptine has been documented to normalize prolactin levels elevated by sulpiride thus taking away the associated side effects. It does not interefere with the action of sulpiride. Pramipexole is also prolactin lowering and won't interfere with the action of sulpiride but I haven't heard of anyone using the combo. I tried amisulpride (cousin of sulpiride) with pramipexole but I didn't experience increased mood, motivation or anything except the best jumpshot I've ever had in my life! Anyway, there is the possibility that the combo of Mirapex and sulpiride will provide additional mood benefit while normalizing your prolactin levels.
>
> BTW, be sure you are using the lowest effective dosage of sulpiride to minimize side effects.
>
> AndrewBHi,
My English is not perfect.
But what does "jumpshot" mean?
Perhaps this question makes you laugh.
Thanks for response
Posted by AndrewB on February 20, 2001, at 22:37:09
In reply to Re: sulpiride » AndrewB, posted by matze on February 20, 2001, at 8:28:13
> Hi,
> My English is not perfect.
> But what does "jumpshot" mean?
> Perhaps this question makes you laugh.
> Thanks for responseJumpshot is a a type of shot at the basket in the game of basketball. To do well it requires good physical coordination.
AndrewB
Posted by MrBrice on March 7, 2006, at 13:25:15
In reply to Re: sulpiride , posted by AndrewB on February 20, 2001, at 22:37:09
I take sulpiride to as a young male (age 20), and i personally don't have that much problems with the decrease in sexual need.
I do think i'm growing breasts tough :) I don't know, maybe it's just imaginary...I take 75mg per day and it really works wonders.
I take it in combination with prothiaden, and those two are supposed to achieve my full recovery according to my p-doc, who i really trust.grtz,
Brice
Posted by ed_uk on March 7, 2006, at 13:47:59
In reply to Re: sulpiride, posted by MrBrice on March 7, 2006, at 13:25:15
Hi
Breast growth in men is an established side effect of sulpiride. It occurs because sulpiride raises the level of a hormone called prolactin.
Ed
This is the end of the thread.
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