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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by maryanne on September 12, 1999, at 14:53:15
I take buspar in high doses for depression. My doctor just added remeron to it. It helps me sleep real good, but I haven't heard of this combination before. Is it OK? A 5HT1 agonist and a 5HT2 antagonist together? Weird. Any comments on this?
Posted by A on September 13, 1999, at 12:05:31
In reply to buspar + remeron, posted by maryanne on September 12, 1999, at 14:53:15
> I take buspar in high doses for depression. My doctor just added remeron to it. It helps me sleep real good, but I haven't heard of this combination before. Is it OK? A 5HT1 agonist and a 5HT2 antagonist together? Weird. Any comments on this?
How high? Did it help your depression--I thought it was for anxiety. Any side effects?
Posted by Jim Spectreman on September 13, 1999, at 20:55:14
In reply to buspar + remeron, posted by maryanne on September 12, 1999, at 14:53:15
Maryanne, I have no doubt in your doctor, but it is important that you do not take too much remeron (over 30mg) while on a high dose of buspirone.
Both of these drugs potentiate serotonin neurotransmission--and you do not want too much serotonin because that can be dangerous.
What do you mean by high doses of buspar anyway? And how much Remeron are you currently taking?
I am a medical student just trying to help. Please post a follow-up if you have questions.
Posted by maryanne on September 14, 1999, at 4:19:03
In reply to Re: buspar + remeron, posted by Jim Spectreman on September 13, 1999, at 20:55:14
> Maryanne, I have no doubt in your doctor, but it is important that you do not take too much remeron (over 30mg) while on a high dose of buspirone.
> Both of these drugs potentiate serotonin neurotransmission--and you do not want too much serotonin because that can be dangerous.
> What do you mean by high doses of buspar anyway? And how much Remeron are you currently taking?
> I am a medical student just trying to help. Please post a follow-up if you have questions.45mg buspar, 15mg remeron. No side effects. 50% improvement of depressive symptoms. I was really just wondering if they would cancel each other out, or whether they would work synergistically?
Posted by dj on September 14, 1999, at 10:08:18
In reply to Re: buspar + remeron, posted by Jim Spectreman on September 13, 1999, at 20:55:14
>
> I am a medical student just trying to help. Please post a follow-up if you have questions.Perhaps you can take a look at my post above about Sour mouth and perhaps you have some suggestions on what a cause for that might be other than reflux. I attempted to e-mail you a query on this at grunter@spectre.com the e-mail address that accompanied your post but it didn't take..Mine will, if you want to follow up directly...
Posted by Jim Spectreman on September 15, 1999, at 21:00:08
In reply to Re: buspar + remeron dosage, posted by maryanne on September 14, 1999, at 4:19:03
For Maryanne, while we are not completely sure, it has been shown
that serotonin drugs (one of which is Remeron) act synergistically
with buspar. They should not cancel out.
Posted by JS on September 15, 1999, at 21:16:34
In reply to Re: query for JS, posted by dj on September 14, 1999, at 10:08:18
DJ,
That's a tough question to answer. If you have not already ruled out reflux, you might try
zantac or pepcid (for example 20mg at bedtime) and see if that helps.
Any situation causing dry mouth could be responsible, but since you're not taking any
anti-depressants, I don't know what the dry mouth is caused by.
Of course, the foods you eat in addition to brushing your teeth AND your tongue 2x a day
is important. You could also try chewing gum or tic-tacs, etc.
Sorry this is so vague.
Posted by dj on September 16, 1999, at 1:26:09
In reply to Re: query for JS, posted by JS on September 15, 1999, at 21:16:34
>.., you might try
> zantac or pepcid (for example 20mg at bedtime) and see if that helps...
> Of course, the foods you eat in addition to brushingJS,
What are zantac & pepcid?
What sort of foods might cause dry mouth? A dentist friend came up with the term keriotosis but that seem to refer to diabetics on a hightly acidic diet...
This is the end of the thread.
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